Despite its importance, understanding the early phases of human development has been
limited by availability of human samples. The recent emergence of stem-cell-derived embryo …

Why researchers should use human embryo models with caution Skip to main content Thank
you for visiting nature.com. You are using a browser version with limited support for CSS. To …

Gastrulation controls the emergence of cellular diversity and axis patterning in the early
embryo. In mammals, this transformation is orchestrated by dynamic signalling centres at the …

High content studies that profile mouse and human embryonic stem cells (m/hESCs) using
various genome-wide technologies such as transcriptomics and proteomics are constantly …

Recent advances in stem-cell technology are now allowing the mechanisms of human
disease to be studied in human cells. A new era for regenerative medicine is arising from …

The NIH Roadmap Epigenomics Mapping Consortium | Nature Biotechnology Skip to main
content Thank you for visiting nature.com. You are using a browser version with limited support …

Implantation of the blastocyst is a developmental milestone in mammalian embryonic
development. At this time, a coordinated program of lineage diversification, cell-fate …

Ontogeny describes the emergence of complex multicellular organisms from single
totipotent cells. This field is particularly challenging in mammals, owing to the indeterminate …

LifeMap Discovery™ provides investigators with an integrated database of embryonic
development, stem cell biology and regenerative medicine. The hand-curated reconstruction …

To understand human development and disease, as well as to regenerate damaged tissues,
scientists are working to engineer certain cell types in vitro and to create 3D …