Modelling human blastocysts by reprogramming fibroblasts into iBlastoids
Human pluripotent and trophoblast stem cells have been essential alternatives to
blastocysts for understanding early human development 1, 2, 3, 4. However, these simple …
blastocysts for understanding early human development 1, 2, 3, 4. However, these simple …
Lineage tracing of human development through somatic mutations
M Spencer Chapman, AM Ranzoni, B Myers… - Nature, 2021 - nature.com
The ontogeny of the human haematopoietic system during fetal development has previously
been characterized mainly through careful microscopic observations. Here we reconstruct a …
been characterized mainly through careful microscopic observations. Here we reconstruct a …
Enabling research with human embryonic and fetal tissue resources
D Gerrelli, S Lisgo, AJ Copp, S Lindsay - Development, 2015 - journals.biologists.com
Congenital anomalies are a significant burden on human health. Understanding the
developmental origins of such anomalies is key to developing potential therapies. The …
developmental origins of such anomalies is key to developing potential therapies. The …