Phototoxicity of ultraviolet (UV) radiation: Evaluation of UV-blocking efficiency of intraocular lens (IOL) materials using retinal cell culture and in vitro bioassays

HY Youn, AP Cullen, C Br… - The Open Toxicology …, 2010 - benthamopen.com
This work involves the evaluation of UV blocking efficiency of commercially available
intraocular lens (IOL) materials using a retinal cell culture and a biological in vitro model that …

Phototoxicity of environmental radiations in human lens: Revisiting the pathogenesis of UV-induced cataract

F Kamari, S Hallaj, F Dorosti, F Alinezhad… - Graefe's Archive for …, 2019 - Springer
The magnitude of cataract pathology is indeed significant as it is the principal cause of
blindness worldwide. Also, the prominence of this concept escalates with the current aging …

[HTML][HTML] In vitro ultraviolet–induced damage in human corneal, lens, and retinal pigment epithelial cells

HY Youn, DJ McCanna, JG Sivak, LW Jones - Molecular vision, 2011 - ncbi.nlm.nih.gov
Purpose The purpose was to develop suitable in vitro methods to detect ocular epithelial cell
damage when exposed to UV radiation, in an effort to evaluate UV-absorbing ophthalmic …

[HTML][HTML] In vitro assays for evaluating the ultraviolet B-induced damage in cultured human retinal pigment epithelial cells

HY Youn, V Bantseev, NC Bols, AP Cullen… - … of Photochemistry and …, 2007 - Elsevier
The present study demonstrates broadband UV-B-induced damage of cultured human
retinal pigment epithelial cells as an effort to develop an in vitro model that can be used …

Impairment of Eye Lens Cell Physiology and Optics by Broadband Ultraviolet A–Ultraviolet B Radiation

OM Oriowo, AP Cullen, JG Sivak - Photochemistry and …, 2002 - Wiley Online Library
The phototoxicity of ultraviolet A (UVA) alone and UVA plus ultraviolet B (UVB) combined on
cultured porcine lenses was investigated by analyzing cellular function as measured with a …

Reliable UV-light protection in intraocular lenses--scientific rationale and quality requirements

AJ Augustin - Klinische Monatsblatter fur Augenheilkunde, 2014 - europepmc.org
Since the late 1980s implantation of UV-blocker intraocular lenses during cataract surgery
has become an internationally accepted standard. Last year the Kassenärztliche …

Prevention of direct and photosensitized ultraviolet radiation damage to the ocular lens

S Lerman, K Gardner, J Megaw, R Borkman - Ophthalmic Research, 1981 - karger.com
Exposure to ambient ultraviolet (UV) radiation (longer than 300 nm) over a lifetime appears
to play a role in lens aging and nuclear cataract formation. The photochemical generation of …

Effects of Light Exposure and Use of Intraocular Lens on Retinal Pigment Epithelial Cells In Vitro

S Hui, L Yi, QL Fengling - Photochemistry and photobiology, 2009 - Wiley Online Library
To investigate the effect of a blue light‐filtering intraocular lens (IOL) and a UV‐absorbing
IOL on light‐induced damage to retinal pigment epithelial (RPE) cells laden with the …

Ultraviolet phototoxicity to the retina

RD Glickman - Eye & contact lens, 2011 - journals.lww.com
Objective: This overview of ultraviolet (UV) phototoxicity considers the interaction of UVA
and short-wavelength VIS light with the retina and retinal pigment epithelium. Methods: The …

Ultraviolet radiation protection

S Lerman - Eye & Contact Lens, 1985 - journals.lww.com
The human ocular lens serves as a natural filter that prevents much ultraviolet (UV) radiation
from penetrating to the more sensitive retina. Indeed, the ocular lens' ability to filter ultraviolet …