One of the key factors that correlates with poor survival of patients with pancreatic cancer is
the extent of hypoxic areas within the tumor tissue. The adaptation of pancreatic cancer cells …

Attributable to its late diagnosis, early metastasis, and poor prognosis, pancreatic cancer
remains one of the most lethal diseases worldwide. Unlike other solid tumors, pancreatic …

Intratumoral hypoxia is a common feature of solid tumors. Recent advances in cancer
biology indicate that hypoxia is not only a consequence of unrestrained tumor growth, but …

Pancreatic cancer (PC) remains one of the most extremely lethal malignancies worldwide
due to late diagnosis and early metastasis, with a 1-year overall survival rate of …

Pancreatic cancer is one of the common malignant tumors of the digestive system and is
known as the “king of cancers”. It is extremely difficult to diagnose at an early stage, the …

Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal solid tumors with
an overall five-year survival rate of that has only just reached 10%. The tumor …

Pancreatic cancer remains a devastating disease. Over the last few years, there have been
important advances in the molecular and biological understanding of pancreatic cancer …

Hypoxia is a common phenomenon in most malignant tumors, especially in pancreatic
cancer (PC). Hypoxia is the result of unlimited tumor growth and plays an active role in …

Pancreatic ductal adenocarcinoma remains one of the most lethal of all solid tumors with an
overall five-year survival rate of only 3–5%. Its aggressive biology and resistance to …

Pancreatic ductal adenocarcinoma (PDA) is a lethal disease with limited response to
cytotoxic chemoradiotherapy, as well as newer immunotherapies. The PDA tumor …