Sex, sleep deprivation, and the anxious brain

AN Goldstein-Piekarski, SM Greer… - Journal of cognitive …, 2018 - direct.mit.edu
Insufficient sleep is a known trigger of anxiety. Nevertheless, not everyone experiences
these effects to the same extent. One determining factor is sex, wherein women experience …

[HTML][HTML] Sleep dysfunction mediates the relationship between hypothalamic-insula connectivity and anxiety-depression symptom severity bidirectionally in young …

G Li, Y Chen, S Chaudhary, CS Li, D Hao, L Yang… - Neuroimage, 2023 - Elsevier
Background The hypothalamus plays a crucial role in regulating sleep-wake cycle and
motivated behavior. Sleep disturbance is associated with impairment in cognitive and …

Self-reported sleep quality modulates amygdala resting-state functional connectivity in anxiety and depression

H Klumpp, B Hosseini, KL Phan - Frontiers in Psychiatry, 2018 - frontiersin.org
Sufficient sleep plays an important role in neurocognitive function, yet, problematic sleep is
ubiquitous in the general population. It is also frequently predictive of, and concurrent with …

Sleep loss and the socio-emotional brain

EB Simon, R Vallat, CM Barnes, MP Walker - Trends in cognitive sciences, 2020 - cell.com
Are you feeling emotionally fragile, moody, unpredictable, even ungenerous to those around
you? Here, we review how and why these phenomena can occur as a result of insufficient …

Losing neutrality: the neural basis of impaired emotional control without sleep

EB Simon, N Oren, H Sharon, A Kirschner… - Journal of …, 2015 - Soc Neuroscience
Sleep deprivation has been shown recently to alter emotional processing possibly
associated with reduced frontal regulation. Such impairments can ultimately fail adaptive …

Association of naturally occurring sleep loss with reduced amygdala resting-state functional connectivity following psychosocial stress

J Nowak, A Dimitrov, NYL Oei, H Walter, M Adli… - …, 2020 - Elsevier
Enduring sleep loss is a risk factor for a variety of both somatic and mental health issues.
When subjected to sleep loss, the brain becomes vulnerable to critical alterations in …

The sleep-deprived human brain

AJ Krause, EB Simon, BA Mander, SM Greer… - Nature Reviews …, 2017 - nature.com
How does a lack of sleep affect our brains? In contrast to the benefits of sleep, frameworks
exploring the impact of sleep loss are relatively lacking. Importantly, the effects of sleep …

Negative emotions and brain: Negative emotions mediates the association between structural and functional variations in emotional-related brain regions and sleep …

L Zhang, Y Bai, X Cui, G Cao, D Li, H Yin - Sleep Medicine, 2022 - Elsevier
Importance and study objective Emotion plays an important role in sleep quality, meanwhile,
poor sleep quality is usually correlated with high negative emotions (NES). However, less is …

Sleep quality and neural circuit function supporting emotion regulation

JD Minkel, K McNealy, PJ Gianaros… - Biology of mood & …, 2012 - Springer
Background Recent laboratory studies employing an extended sleep deprivation model
have mapped sleep-related changes in behavior onto functional alterations in specific brain …

Sleep debt elicits negative emotional reaction through diminished amygdala-anterior cingulate functional connectivity

Y Motomura, S Kitamura, K Oba, Y Terasawa… - PloS one, 2013 - journals.plos.org
Objectives Sleep debt reportedly increases emotional instability, such as anxiety and
confusion, in addition to sleepiness and psychomotor impairment. However, the neural basis …