Surface‐deposited pathogens are sources for the spread of infectious diseases. Protecting
public facilities with a replaceable or recyclable antifouling coating is a promising approach …

Mucus linings serve as the body's first line of defense at exposed surfaces of the eye and
respiratory, gastrointestinal, and cervicovaginal tracts. The high viscoelasticity and …

The intestinal mucus gel layer represents a stumbling block for drug adsorption. This study is
aimed to formulate a nanoparticulate system able to overcome this barrier by cleaving …

Allergic rhinitis (AR) was a chronic airway inflammatory disease. Nasal administration
showed superiorities due to its effective drug absorption. Cetirizine (CTZ) was a common H …

Severe pneumonia caused by bacteria remains a serious clinical challenge, because the
mucus in the lower respiratory tract hinders the effective utilization of antibiotics. Thus, drug …

We previously developed a safe and effective nasal vaccine delivery system using a self-
assembled nanosized hydrogel (nanogel) made from a cationic cholesteryl pullulan. Here …

Neutrophil elastase (NE) is a major protease in the airways of patients with cystic fibrosis
(CF) that activates airway inflammation by several mechanisms. NE stimulates epithelial toll …

Mucus-penetrating Nanosuspensions, consisting of pure hydrophobic therapeutics with
dense muco-inert coatings that enable particles to effectively bypass the mucus barrier …

Although angiogenesis is a hallmark feature of asthmatic inflammatory responses,
therapeutic anti-angiogenesis interventions have received little attention. Objective: Assess …

Asthma is a common chronic inflammatory disease associated with intermittent airflow
obstruction caused by airway inflammation, mucus overproduction, and bronchial …