Acute lung injury (ALI) is one of the most common comorbidities associated with sepsis and
can lead to acute respiratory distress syndrome. Intense inflammatory response due to …

Abstract Treatment of inflammatory disorders with glucocorticoids (GCs) is often
accompanied by severe adverse effects. Application of GCs via nanoparticles (NPs) …

Intranasal administration of nano-drug-delivery systems emerged as an appealing strategy
to surpass the blood–brain barrier and thus increase drug bioavailability in the central …

The purpose of this research was to prepare spray-dried mucoadhesive microspheres for
nasal delivery. Microspheres composed of hydroxypropyl methylcellulose (H), chitosan (CS) …

Efficient mucosal delivery remains a major challenge for the reason of the respiratory tract
mucus act as a formidable barrier to nanocarriers by trapping and clearing foreign …

Dendrimer micelles with glycyrrhizic acid (GA) were developed for anti-inflammatory therapy
of acute lung injury (ALI). Cholesterol was conjugated to histidine-and arginine-grafted …

An effective specific immunotherapy should contain elements to generate specific
recognition (T-cell peptides) and to modulate the immunological response towards a …

Inhaled nanoparticles (NPs) need to penetrate the bronchial mucosa to deliver drug
payloads deeply in the lung for amplified local therapy. However, the bronchial mucociliary …

The objective of the present study was to develop n-propyl gallate-loaded solid lipid
nanoparticles (PG-SLNs) in a hydrogel (HG) formulation using Transcutol-P (TC-P) as a …

Among respiratory infections, tuberculosis was the second deadliest infectious disease in
2020 behind COVID-19. Inhalable nanocarriers offer the possibility of actively targeting anti …