The field of extracellular nucleotides and purinoceptors has undergone a resurgence of
interest and enthusiasm in the past decade. More and more investigators are probing the …

Background and purpose: Extracellular nucleotides play a crucial role in the regulation of
vascular tone and blood flow. Stimulation of endothelial cell P2Y1 receptors evokes …

1. Diadenosine phosphates were isolated from platelets, adrenal gland and autonomic
nerves. The presence of diadenosine phosphates in storage pools releasable into the …

Diadenosine pentaphosphate and diadenosine hexaphosphate have been isolated in
human platelets and have been postulated to play an important role in the control of …

The hypothesis that ATP and ADP produce dilations of rat middle cerebral arteries (MCAs)
by different mechanisms was tested. Vessel diameters were measured from pressurized …

The effects of dipyridamole and adenosine on the renal vasculature and on the
enhancement by dipyridamole of the action of adenosine were studied in pigs, dogs, rabbits …

Adenosine triphosphate (ATP) and norepinephrine (NE) interact in the control of blood flow
in the kidney. A combined effect of NE and ATP has not been previously investigated at the …

1 P2‐purinoceptors were characterized pharmacologically in the constantly perfused
isolated mesenteric arterial vascular bed of the golden hamster. Vasoconstrictor and …

Extracellular nucleotides, acting through P 2-purinoceptors, have been implicated in the
regulation of ion transport in epithelia, including Madin-Darby canine kidney (MDCK) cells …

Experiments were performed in pentobarbital sodium-anesthetized rats to determine the
effects of activation of P2 purinoceptors sensitive to ATP on glomerular capillary pressure, as …