In 1996, we reported a method for utilizing biomolecules, such as DNA, and their molecular
recognition properties to guide the assembly of nanoparticle building blocks modified with …

Here, we synthesized highly stable DNA-embedded Au/Ag core–shell nanoparticles (NPs)
by a straightforward silver-staining of DNA-modified Au nanoparticles (AuNPs); unlike …

We have determined the minimum number of base pairings necessary to stabilize DNA− Au
NP aggregates as a function of salt concentration for particles between 15 and 150 nm in …

This unit describes the preparation of conjugates between nanometer‐scale gold particles
and synthetic oligonucleotides. Oligonucleotide‐functionalized gold nanoparticles are …

Herein, we describe the detailed synthesis of Ag/Au core-shell nanoparticles, the surface-
functionalization of these particles with thiolated oligonucleotides, and their subsequent use …

A study aimed at understanding the factors that control the optical properties of DNA-linked
gold nanoparticle aggregates containing oligonucleotide linkers of varying length (24− 72 …

Glutathione monolayer-protected gold clusters were reacted by place exchange with 19-or
20-residue thiolated oligonucleotides. The resulting DNA/nanoparticle conjugates could be …

Monovalent DNA–gold nanoparticle (mDNA–AuNP) conjugates hold great promise for
widespread applications, especially the construction of well-defined, molecule-like …

We find that single-and double-stranded oligonucleotides have different propensities to
adsorb on gold nanoparticles in colloidal solution. We use this observation to design a …

Colloidal gold nanocrystals have been used to develop a new class of nanobiosensors that
is able to recognize and detect specific DNA sequences and single-base mutations in a …