Ejection fraction: misunderstood and overrated (changing the paradigm in categorizing heart failure)

MA Konstam, FM Abboud - Circulation, 2017 - Am Heart Assoc
February 21, 2017 Circulation. 2017; 135: 717–719. DOI: 10.1161/CIRCULATIONAHA.
116.025795 718 pertrophic cardiomyopathy (28%), which encroaches on the LV cavity in …

Phenotypic and pathophysiological heterogeneity in heart failure with preserved ejection fraction

AM Shah, SD Solomon - European heart journal, 2012 - academic.oup.com
This editorial refers to 'Discriminating clinical features of heart failure with preserved vs.
reduced ejection fraction in the community'†, by JE Ho et al., on page 1734 and 'Diastolic …

The many faces of heart failure with preserved ejection fraction

AM Shah, MA Pfeffer - Nature Reviews Cardiology, 2012 - nature.com
By definition, patients with heart failure and preserved ejection fraction are characterized by
a normal or near-normal left ventricular ejection fraction, but marked heterogeneity in the …

The pathophysiology of heart failure with preserved ejection fraction

BA Borlaug - Nature Reviews Cardiology, 2014 - nature.com
Approximately half of all patients with heart failure have preserved ejection fraction (HFpEF)
and, as life expectancies continue to increase in western societies, the prevalence of HFpEF …

Heart failure with preserved ejection fraction: recent concepts in diagnosis, mechanisms and management

AB Gevaert, R Kataria, F Zannad, AJ Sauer, K Damman… - Heart, 2022 - heart.bmj.com
It is estimated that half of all patients with heart failure (HF) have HF with preserved ejection
fraction (HFpEF). Yet this form of HF remains a diagnostic and therapeutic challenge …

Routinely reported ejection fraction and mortality in clinical practice: where does the nadir of risk lie?

GJ Wehner, L Jing, CM Haggerty… - European heart …, 2020 - academic.oup.com
Aims We investigated the relationship between clinically assessed left ventricular ejection
fraction (LVEF) and survival in a large, heterogeneous clinical cohort. Methods and results …

Heart failure with reduced ejection fraction

MW Bloom, B Greenberg, T Jaarsma… - Nature reviews Disease …, 2017 - nature.com
Heart failure is a global public health problem that affects more than 26 million people
worldwide. The global burden of heart failure is growing and is expected to increase …

What have we learned about heart failure with mid‐range ejection fraction one year after its introduction?

JF Nauta, YM Hummel, JP van Melle… - European journal of …, 2017 - Wiley Online Library
The 2016 European Society of Cardiology heart failure guidelines introduced the term 'heart
failure with mid‐range ejection fraction'(HFmrEF) to refer to patients with heart failure and a …

Characteristics of heart failure with preserved ejection fraction across the range of left ventricular ejection fraction

S Rosch, KP Kresoja, C Besler, K Fengler… - Circulation, 2022 - Am Heart Assoc
Background: Recent trial data suggest that stratification of patients with heart failure with
preserved ejection fraction (HFpEF) according to left ventricular ejection fraction (LVEF) …

Beyond ejection fraction: an integrative approach for assessment of cardiac structure and function in heart failure

M Cikes, SD Solomon - European heart journal, 2016 - academic.oup.com
Left ventricular ejection fraction (LVEF) has been the central parameter used for diagnosis
and management in patients with heart failure. A good predictor of adverse outcomes in …