Sialic acid is an important component of cell surface glycans, which are responsible for
many vital body functions and should therefore be thoroughly studied to understand their …

Sialic acids on the non-reducing terminus of sialylgylcans are abundantly expressed on the
surface of mammalian cells. They play vital roles in cell-cell interactions and during infection …

Highlights•Chemical synthesis provided access to O-linked and S-linked oligosialic
acids.•Oxazolidinone-protected sialyl donors enable α-selective sialylation.•Enzymatic …

The stereoselective synthesis of sialosides is still one of the major challenges in
carbohydrate chemistry. The synthesis and glycosidation of novel sialyl donors bearing a …

Sialic acid‐containing glycans play important roles in biology, but their synthesis by
standard chemical approaches is challenging. Enzymatic assembly is generally a better …

Sialoglycans play a vital role in physiology, and aberrant sialoglycan expression is
associated with a broad spectrum of diseases. Since biosynthesis of sialoglycans is only …

The installation of the novel N, N-dimethylglycolamide ester auxiliary onto the C (1)-position
of protected neuraminic acid donors allows for the exploitation of C (1)-neighboring group …

Conspectus Sialic acids are fascinating negatively charged nine-carbon monosaccharides.
Sialic acid-containing glycans and glycoconjugates are structurally diverse, functionally …

The ongoing studies on oligosaccharide synthesis have resulted in the development of
precise synthetic methods by which a large portion of the complex natural oligosaccharides …

O-Acetylation of sialic acid (Sia) modulates its recognition by sialic acid-binding proteins and
plays an important role in biological and pathological processes. 9-O-Acetylation is the most …