Molecular cloning and characterization of three β-defensins from canine testes

Y Sang, MT Ortega, F Blecha, O Prakash… - Infection and …, 2005 - Am Soc Microbiol
Mammalian β-defensins are small cationic peptides possessing broad antimicrobial and
physiological activities. Because dogs are particularly resilient to sexually transmitted …

[HTML][HTML] Antibacterial activity of human defensins on anaerobic intestinal bacterial species: a major role of HBD-3

S Nuding, LT Zabel, C Enders, E Porter… - Microbes and …, 2009 - Elsevier
Defensins are natural mucosal antimicrobial peptides and their broad spectrum activity
against aerobic or facultative anaerobic bacteria has been well investigated. The aim of this …

Induction of Human β-Defensin 2 by the Probiotic Escherichia coli Nissle 1917 Is Mediated through Flagellin

M Schlee, J Wehkamp, A Altenhoefer… - Infection and …, 2007 - Am Soc Microbiol
ABSTRACT Human β-defensin 2 (hBD-2) is an inducible antimicrobial peptide synthesized
by the epithelium to counteract bacterial adherence and invasion. Proinflammatory …

[HTML][HTML] Novel synthetic analogues of avian β-defensin-12: the role of charge, hydrophobicity, and disulfide bridges in biological functions

M Yang, C Zhang, MZ Zhang, S Zhang - BMC microbiology, 2017 - Springer
Abstract Background Avian β-defensins (AvBD) possess broad-spectrum antimicrobial, LPS
neutralizing and chemotactic properties. AvBD-12 is a chemoattractant for avian immune …

[HTML][HTML] Identification and biological characterization of mouse β-defensin 14, the orthologue of human β-defensin 3

J Rohrl, D Yang, JJ Oppenheim, T Hehlgans - Journal of biological …, 2008 - ASBMB
β-Defensins are small antimicrobial polypeptides that are mainly expressed by epithelial
cells and play an important role in the antimicrobial innate immune response. In addition to …

[HTML][HTML] Significance of human β-defensins in the epithelial lining fluid of patients with chronic lower respiratory tract infections

S Yanagi, J Ashitani, K Imai, Y Kyoraku, A Sano… - Clinical microbiology …, 2007 - Elsevier
Human β-defensins (hBDs) are the most abundant antimicrobial peptides in epithelial cells,
and function in the host immune system. Respiratory epithelial cells express hBDs to inhibit …

Discovery and characterization of Coturnix chinensis avian β‐defensin 10, with broad antibacterial activity

D Ma, L Lin, K Zhang, Z Han, Y Shao… - Journal of peptide …, 2012 - Wiley Online Library
A novel avian β‐defensin (AvBD), AvBD10, was discovered in the liver and bone marrow
tissues from Chinese painted quail (Coturnix chinensis) in the present study. The complete …

[HTML][HTML] Antimicrobial human β-defensins in the colon and their role in infectious and non-infectious diseases

ER Cobo, K Chadee - Pathogens, 2013 - mdpi.com
β-defensins are small cationic antimicrobial peptides secreted by diverse cell types
including colonic epithelial cells. Human β-defensins form an essential component of the …

[HTML][HTML] Molecular cloning and tissue expression of porcine β-defensin-1

G Zhang, H Wu, J Shi, T Ganz, CR Ross, F Blecha - FEBS letters, 1998 - Elsevier
Beta-defensins constitute an emerging family of cysteine-rich antimicrobial peptides, which
are particularly prominent at mucosal epithelial sites in mammals. Here we report the …

[HTML][HTML] Analysis and separation of residues important for the chemoattractant and antimicrobial activities of β-defensin 3

K Taylor, DJ Clarke, B McCullough, W Chin… - Journal of biological …, 2008 - ASBMB
β-Defensins are important in mammalian immunity displaying both antimicrobial and
chemoattractant activities. Three canonical disulfide intramolecular bonds are believed to be …