[PDF][PDF] Neuroprotecive effect of early treatment with pioglitasone and methylcobalamin in alloxan induced diabetes in rats

AS Morani, SL Bodhankar - Pharmacologyonline, 2007 - pharmacologyonline.silae.it
Neuropathic pain in diabetics is characterized by both hyperalgesia and allodynia. This is
attributed to both uncontrolled glycemia and the further complications which it leads to. We …

[PDF][PDF] Neuroprotective effect of early treatment with pioglitasone and vitamin E acetate in alloxan induced diabetes in rats

AS Morani, SL Bodhankar - Pharmacologyonline, 2007 - pharmacologyonline.silae.it
Neuropathic pain in diabetics is characterized by both hyperalgesia and allodynia. This is
attributed to both uncontrolled glycemia and the further complications which it leads to. We …

[PDF][PDF] Neuroprotective effect of early treatment with pioglitazone and pyridoxine hydrochloride in alloxan induced diabetes in rats

AS Morani, SL Bodhankar - Pharmacol online, 2007 - researchgate.net
Neuropathic pain in diabetics is characterized by both hyperalgesia and allodynia. This is
attributed to both uncontrolled glycemia and the further complications which it leads to. We …

A neuroprotective effect of pentoxifylline in rats with diabetic neuropathy: Mitigation of inflammatory and vascular alterations

RAM Salama, FA Raafat, AH Hasanin… - International …, 2024 - Elsevier
Background Treatment of diabetic neuropathic pain does not change the natural history of
neuropathy. Improved glycemic control is the recommended treatment in these cases, given …

[HTML][HTML] Synergism between metformin and analgesics/vitamin B12 in a model of painful diabetic neuropathy

U Pecikoza, M Tomić, K Nastić, A Micov… - Biomedicine & …, 2022 - Elsevier
Metformin (a widely used antidiabetic drug) has demonstrated efficacy in models of painful
diabetic neuropathy (PDN), as well as certain clinical efficacy in relieving/preventing PDN …

[PDF][PDF] INVESTIGATION OF ANTIHYPERALGESIC EFFECTS OF DIFFERENT DOSES OF SILDENAFIL AND METFORMIN IN ALLOXAN-INDUCED DIABETIC …

C PUȘCAȘU, DP MIHAI, CE ZBÂRCEA… - …, 2023 - farmaciajournal.com
Neuropathy is one of the most frequent and continuously growing complications of diabetes.
Due to the multitude of mechanisms involved in the pathogenesis of diabetic neuropathy …

Anti-hypernociceptive and anti-oxidative effects of locally treated dobutamine in diabetic rats

T Mert, H Oksuz, B Tugtag, M Kilinc, E Sahin… - Pharmacological …, 2015 - Elsevier
Background Oxidative stress as a significant factor in the development of diabetes induced
neuropathic pain as well as the potential for prevention of this complication. Therefore, we …

[PDF][PDF] Effects of melatonin and vitamin E on peripheral neuropathic pain in streptozotocin-induced diabetic rats

BF BABAEI, S Zare, R HEYDARI, F Farokhi - 2010 - sid.ir
Objective (s): Previous studies have indicated that diabetes mellitus might be accompanied
by neuropathic pain. Oxidative stress is implicated as a final common pathway in …

Evaluating the Antihyperalgesic Potential of Sildenafil–Metformin Combination and Its Impact on Biochemical Markers in Alloxan-Induced Diabetic Neuropathy in Rats

C Pușcașu, S Negreș, CE Zbârcea, A Ungurianu… - Pharmaceuticals, 2024 - mdpi.com
(1) Background: Globally, about 600 million people are afflicted with diabetes, and one of its
most prevalent complications is neuropathy, a debilitating condition. At the present time, the …

Glycemic control and pain threshold in alloxan diabetic rats

GF Ibironke, OJ Saba, FO Olopade - African journal of biomedical research, 2004 - ajol.info
Insulin dependent diabetes mellitus (IDDM) is associated with several complications
including painful diabetic neuropathy. Previous animal and human studies have indicated …