BaoShenTongLuo formula protects against podocyte injury by regulating AMPK-mediated mitochondrial biogenesis in diabetic kidney disease
Y Guo, M Wang, Y Liu, Y Pang, L Tian, J Zhao, M Liu… - Chinese Medicine, 2023 - Springer
Background Mitochondrial dysfunction is considered to be an important contributor in
podocyte injury under diabetic conditions. The BaoShenTongLuo (BSTL) formula has been …
podocyte injury under diabetic conditions. The BaoShenTongLuo (BSTL) formula has been …
Mechanisms of herbal nephroprotection in diabetes mellitus
Diabetic nephropathy (DN) is a leading cause of kidney morbidity. Despite the multilayered
complexity of the mechanisms involved in the pathogenesis of DN, the conventional …
complexity of the mechanisms involved in the pathogenesis of DN, the conventional …
Diabetes cardiomyopathy: targeted regulation of mitochondrial dysfunction and therapeutic potential of plant secondary metabolites
X Pan, E Hao, F Zhang, W Wei, Z Du, G Yan… - Frontiers in …, 2024 - frontiersin.org
Diabetic cardiomyopathy (DCM) is a specific heart condition in diabetic patients, which is a
major cause of heart failure and significantly affects quality of life. DCM is manifested as …
major cause of heart failure and significantly affects quality of life. DCM is manifested as …
Chinese herbal medicine in ameliorating diabetic kidney disease via activating autophagy
Y Wang, H Zhao, Q Wang, X Zhou, X Lu… - Journal of diabetes …, 2019 - Wiley Online Library
Diabetic kidney disease (DKD), a leading cause of end‐stage renal disease (ESRD), has
become a serious public health problem worldwide and lacks effective therapies due to its …
become a serious public health problem worldwide and lacks effective therapies due to its …
Astragaloside IV alleviates 1-deoxysphinganine-induced mitochondrial dysfunction during the progression of chronic kidney disease through p62-Nrf2 antioxidant …
T Gui, Q Chen, J Li, K Lu, C Li, B Xu, Y Chen… - Frontiers in …, 2023 - frontiersin.org
Introduction: Chronic kidney disease (CKD) can lead to significant elevation of 1-
deoxysphingolipids (1-deoxySL). The increase of 1-deoxySL in turn can result in …
deoxysphingolipids (1-deoxySL). The increase of 1-deoxySL in turn can result in …
Melatonin attenuates renal fibrosis in diabetic mice by activating the AMPK/PGC1α signaling pathway and rescuing mitochondrial function
J Li, N Li, S Yan, Y Lu, X Miao… - Molecular medicine …, 2019 - spandidos-publications.com
Mitochondrial homeostasis is a highly regulated process that serves a critical role in the
maintenance of renal structure and function. The growing interest in the field of …
maintenance of renal structure and function. The growing interest in the field of …
Protective effects of purple rice husk against diabetic nephropathy by modulating PGC-1α/SIRT3/SOD2 signaling and maintaining mitochondrial redox equilibrium in …
O Wongmekiat, N Lailerd, A Kobroob… - Biomolecules, 2021 - mdpi.com
Diabetic nephropathy (DN) is the primary cause of end-stage renal disease worldwide.
Oxidative stress and mitochondrial dysfunction are central to its pathogenesis. Rice husk …
Oxidative stress and mitochondrial dysfunction are central to its pathogenesis. Rice husk …
Berberine reduces lipid accumulation by promoting fatty acid oxidation in renal tubular epithelial cells of the diabetic kidney
Abnormal lipid metabolism in renal tubular epithelial cells contributes to renal lipid
accumulation and disturbed mitochondrial bioenergetics which are important in diabetic …
accumulation and disturbed mitochondrial bioenergetics which are important in diabetic …
Mechanistic insight of diabetic nephropathy and its pharmacotherapeutic targets: an update
N Bhattacharjee, S Barma, N Konwar… - European journal of …, 2016 - Elsevier
Diabetic nephropathy (DN), a chronic complication of diabetes, is charecterized by
glomerular hypertrophy, proteinuria, decreased glomerular filtration, and renal fibrosis …
glomerular hypertrophy, proteinuria, decreased glomerular filtration, and renal fibrosis …
Mitochondrial contribution to inflammation in diabetic kidney disease
A Mitrofanova, AM Fontanella, GW Burke, S Merscher… - Cells, 2022 - mdpi.com
Diabetes is the leading cause of chronic kidney disease worldwide. Despite the burden, the
factors contributing to the development and progression of diabetic kidney disease (DKD) …
factors contributing to the development and progression of diabetic kidney disease (DKD) …