[PDF][PDF] Innate immunity and IgA nephropathy

R Coppo, A Amore, L Peruzzi, L Vergano… - JN journal of …, 2010 - researchgate.net
The hallmark of IgA nephropathy (IgAN) is macroscopic hematuria coinciding with, or
immediately following, a mucosal infection, usually of the upper respiratory airways. The role …

Does the renal expression of Toll-like receptors play a role in patients with IgA nephropathy?

H Ciferska, E Honsova, A Lodererova, Z Hruskova… - Journal of …, 2020 - Springer
The onset of IgA nephropathy (IgAN), characterized by glomerular deposition of IgA-
containing immune complexes, is often associated with synpharyngitic hematuria. Innate …

Nasal-associated lymphoid tissue is the major induction site for nephritogenic IgA in murine IgA nephropathy

T Kano, H Suzuki, Y Makita, Y Fukao, Y Suzuki - Kidney international, 2021 - Elsevier
Dysregulation of mucosal immunity may play a role in the pathogenesis of IgA nephropathy
(IgAN). However, it is unclear whether the nasal-associated lymphoid tissue (NALT) or gut …

The gut and kidney crosstalk in immunoglobulin A nephropathy

L Sanchez-Russo, A Rajasekaran, S Bin, J Faith… - Kidney360, 2022 - journals.lww.com
Immunoglobulin A nephropathy (IgAN) is the most common primary glomerulonephritis
worldwide. The working model for the pathogenesis of IgAN involves a multistep process …

Mucosal immune system dysregulation in the pathogenesis of IgA nephropathy

T Kano, H Suzuki, Y Makita, Y Nihei, Y Fukao… - Biomedicines, 2022 - mdpi.com
The mucosal immune system, via a dynamic immune network, serves as the first line of
defense against exogenous antigens. Mucosal immune system dysregulation is closely …

The mucosal immune system and IgA nephropathy

L Gesualdo, V Di Leo, R Coppo - Seminars in immunopathology, 2021 - Springer
The precise pathogenesis of immunoglobulin A nephropathy (IgAN) is still not clearly
established but emerging evidence confirms a pivotal role for mucosal immunity. This review …

The role of immune modulation in pathogenesis of IgA nephropathy

S Chang, XK Li - Frontiers in Medicine, 2020 - frontiersin.org
IgA nephropathy (IgAN) is the most prevalent primary glomerulonephritis worldwide, with
diverse clinical manifestations characterized by recurrent gross hematuria or microscopic …

The mucosa–kidney axis in IgA nephropathy

J Floege, J Feehally - Nature Reviews Nephrology, 2016 - nature.com
Abstract Links between IgA nephropathy (IgAN) and the mucosa have been recognized
since the 1970s. In particular, the observation of visible haematuria induced by respiratory …

Gut-kidney axis in IgA nephropathy: Role on mesangial cell metabolism and inflammation

MJ Luvizotto, L Menezes-Silva, V Woronik… - Frontiers in Cell and …, 2022 - frontiersin.org
IgA Nephropathy (IgAN) is the commonest primary glomerular disease around the world and
represents a significant cause of end-stage renal disease. IgAN is characterized by …

Immunological drivers of IgA nephropathy: Exploring the mucosa–kidney link

H Selvaskandan, J Barratt… - International Journal of …, 2022 - Wiley Online Library
IgA nephropathy (IgAN) is the most common pattern of primary glomerular disease reported
worldwide. Up to 40% of those with IgAN progress to end‐stage kidney disease within 20 …