Mitochondria are critical for maintaining normal cardiac function, and a deficit in
mitochondrial energetics can lead to the development of the substrate that promotes atrial …

Background Atrial fibrillation (AF) and heart failure (HF) commonly coexist, yet the molecular
mechanisms of this association have not been determined. We hypothesized that an energy …

Accumulating evidence links calcium-overload and oxidative stress to atrial remodeling
during atrial fibrillation (AF). Furthermore, atrial remodeling appears to increase atrial …

Atrial fibrillation (AF) is the most common and significant cardiac arrhythmia in clinical
practice, however the pathophysiological mechanism of AF has not been fully explained. At …

Objectives: This study sought to provide bedside evidence of the potential link between
cardiac mitochondrial dysfunction and arrhythmia as reported in bench studies. Background …

Atrial fibrillation (AF) is the most prevalent and progressive cardiac arrhythmia worldwide
and is associated with serious complications such as heart failure and ischemic stroke …

Objectives Type 2 diabetes mellitus is a chronic progressive disease that is associated with
increased risk for cardiovascular diseases and with impaired mitochondrial metabolism in …

Despite the enormous progress in the treatment of atrial fibrillation, mainly with the use of
invasive techniques, many questions remain unanswered regarding the pathomechanism of …

Atrial fibrillation (AF) is a cardiac arrhythmia caused by electrophysiological anomalies in the
atrial tissue, tissue degradation, structural abnormalities, and comorbidities. A direct …

Atrial fibrillation (AF) is the most common type of cardiac arrhythmia and its prevalence
increases with age. The irregular and rapid contraction of the atria can lead to ineffective …