We have studied gut mucosal perfusion in 24 infants, aged 0.7-45 weeks, requiring
cardiopulmonary bypass (CPB). Group 2 patients (n= 12) had received the angiotensin …

OBJECTIVES: Cardiopulmonary bypass surgery is complicated by metabolic acidosis,
microvascular dysfunction, and capillary leak. The glycocalyx—a layer of proteins and …

Microcirculatory dysfunction plays a key role in the pathophysiology of various disease
states and may consequently impact patient outcome. Until recently, the evaluation of the …

OBJECTIVE: Complications after cardiac surgery may involve multiple organ failure, which
carries a high mortality. Development of multiple organ failure may be related to impaired …

Objective Procedural sedation with propofol is widely used in the pediatric population. A well‐
known side effect of propofol is a decrease in peripheral vascular resistance resulting in …

Purpose: Microvascular perfusion, pivotal for adequate tissue oxygenation is potentially
linked to outcome in critical care therapy. Mechanical ventilation (MV) and positive end …

Objectives: Orthogonal polarized spectral imaging-and sidestream darkfield-technique have
enabled visual evaluation of the microcirculation. Different investigators described …

We studied gut mucosal perfusion in 24 neonates requiring cardiopulmonary bypass (CPB).
Group A patients (n= 12) had obstruction to their aorta such that gut perfusion before …

Hypoperfusion of splanchnic organs is an important contributor to the development of
multiple organ failure after major surgery and trauma. During general anaesthesia and …

Background Real-time automated analysis of videos of the microvasculature is an essential
step in the development of research protocols and clinical algorithms that incorporate point …