Inflammation in abdominal aortic aneurysms: cellular infiltrate and cytokine profiles

MJ Eagleton - Vascular, 2012 - journals.sagepub.com
Abdominal aortic aneurysm (AAA) pathogenesis occurs as a result of the altered
homeostasis of the aortic vessel wall structural proteins. This results in weakening, and …

Aortic wall inflammation in the pathogenesis, diagnosis and treatment of aortic aneurysms

G Skotsimara, A Antonopoulos, E Oikonomou… - Inflammation, 2022 - Springer
The role of inflammation in the development of aortic aneurysms is emerging, along with the
potential diagnostic and therapeutical potential of this correlation. Abdominal aorta …

Monocytes and macrophages in abdominal aortic aneurysm

J Raffort, F Lareyre, M Clément… - Nature Reviews …, 2017 - nature.com
Abdominal aortic aneurysm (AAA) is a life-threatening disease associated with high
morbidity, and high mortality in the event of aortic rupture. Major advances in open surgical …

[HTML][HTML] Abdominal aortic aneurysm: roles of inflammatory cells

Z Yuan, Y Lu, J Wei, J Wu, J Yang, Z Cai - Frontiers in immunology, 2021 - frontiersin.org
Abdominal aortic aneurysms (AAAs) are local dilations of infrarenal segment of aortas.
Molecular mechanisms underlying the pathogenesis of AAA remain not fully clear. However …

Inflammation and cellular immune responses in abdominal aortic aneurysms

K Shimizu, RN Mitchell, P Libby - Arteriosclerosis, thrombosis, and …, 2006 - Am Heart Assoc
Expansion and rupture of abdominal aortic aneurysms (AAA) result in high morbidity and
mortality rates. Like stenotic atherosclerotic lesions, AAA accumulate inflammatory cells, but …

Enhanced expression and activation of pro-inflammatory transcription factors distinguish aneurysmal from atherosclerotic aorta: IL-6-and IL-8-dominated inflammatory …

JHN Lindeman, H Abdul-Hussien… - Clinical …, 2008 - portlandpress.com
Inflammation plays a key role in the pathogenesis of an AAA (abdominal aortic aneurysm);
however, the nature of the inflammatory factors and cellular response (s) involved in AAA …

Abdominal aortic aneurysms: an autoimmune disease?

VP Jagadesham, DJA Scott, SR Carding - Trends in molecular medicine, 2008 - cell.com
Abdominal aortic aneurysms (AAAs) are a multifactorial degenerative vascular disorder. One
of the defining features of the pathophysiology of aneurysmal disease is inflammation …

Abdominal aortic aneurysms: fresh insights from a novel animal model of the disease

MW Manning, LA Cassis, J Huang… - Vascular …, 2002 - journals.sagepub.com
Abdominal aortic aneurysms (AAA) have a high prevalence in aged populations and are
responsible for a large number of deaths. Despite the widespread nature of the disease …

Modulation of immune‐inflammatory responses in abdominal aortic aneurysm: Emerging molecular targets

H Li, S Bai, Q Ao, X Wang, X Tian, X Li… - Journal of …, 2018 - Wiley Online Library
Abdominal aortic aneurysm (AAA), a deadly vascular disease in human, is a chronic
degenerative process of the abdominal aorta. In this process, inflammatory responses and …

Inflammatory cell phenotypes in AAAs: their role and potential as targets for therapy

MA Dale, MK Ruhlman, BT Baxter - … , thrombosis, and vascular …, 2015 - Am Heart Assoc
Abdominal aortic aneurysms (AAAs) are characterized by chronic inflammatory cell
infiltration. AAA is typically an asymptomatic disease and caused≈ 15 000 deaths annually …