Computational modeling of biological systems have gained a lot of interest in biomedical
research, in the recent past. This thesis focuses on the application of computational …

Airborne particle pollution causes a range of respiratory and cardiovascular disorders by
entering the human respiratory system through the breathing process. The administration of …

This study aims to systematically isolate different anatomical features of the human pharynx
with the goal to investigate their independent influence on airflow dynamics and particle …

In the present study, unsteady airflow patterns and particle deposition in healthy human
upper airways were simulated. A realistic 3-D computational model of the upper airways …

People may inhale 100 millions of particles each day, including toxic particulate matter as
well as drug aerosols. Some of those deposited in the respiratory system can be either …

Abstract Background and Objective Health care costs represent a substantial an increasing
percentage of global expenditures. One key component is treatment of respiratory diseases …

Accurate assessment and prediction of airflow dynamics and particle deposition in the
human respiratory tract are essential for human health, involving inhaled drugs for treating …

Targeted drug delivery is an advanced method discussed in the literature for optimized
treatment of diseases. However, the data for a precise understanding of pharmaceutical …

This study presents a new combined computational and experimental platform capable of
providing detailed information on upper airway particle transport. The work presents the …

Objectives For dry powder inhalers, the airflow properties in the airways could affect the
deposition of inhaled particles; the flow patterns vary inherently between patients. This …