Trans-but not Cis-resveratrol impairs angiotensin-II–mediated vascular inflammation through inhibition of NF-κB activation and peroxisome proliferator-activated …

C Rius, M Abu-Taha, C Hermenegildo… - The Journal of …, 2010 - journals.aai.org
Abstract Angiotensin II (Ang-II) displays inflammatory activity and is implicated in several
cardiovascular disorders. This study evaluates the effect of cis-and trans (t)-resveratrol …

[HTML][HTML] Natural compound resveratrol attenuates TNF-alpha-induced vascular dysfunction in mice and human endothelial cells: the involvement of the NF-κB …

P Nallasamy, ZY Kang, X Sun… - International Journal of …, 2021 - mdpi.com
Resveratrol, a natural compound in grapes and red wine, has drawn attention due to
potential cardiovascular-related health benefits. However, its effect on vascular inflammation …

Resveratrol attenuates TNF-α-induced activation of coronary arterial endothelial cells: role of NF-κB inhibition

A Csiszar, K Smith, N Labinskyy… - American Journal …, 2006 - journals.physiology.org
Epidemiological studies suggest that Mediterranean diets rich in resveratrol are associated
with reduced risk of coronary artery disease. However, the mechanisms by which resveratrol …

Antiatherogenic effect of resveratrol attributed to decreased expression of ICAM-1 (Intercellular adhesion Molecule-1) mechanistic link from focal adhesion to …

Y Seo, J Park, W Choi, D Ju Son… - … , and vascular biology, 2019 - Am Heart Assoc
Objective—Increasing evidence shows that resveratrol has antiatherogenic effects, but its
underlying mechanisms are unknown. Thus, we evaluated the molecular mechanisms …

Resveratrol prevents TNF-α-induced VCAM-1 and ICAM-1 upregulation in endothelial progenitor cells via reduction of NF-κ B activation

Y Zhang, H Liu, W Tang, Q Qiu… - Journal of International …, 2020 - journals.sagepub.com
Objective To assess the effects of resveratrol (RSV) on expression of adhesion molecules in
endothelial progenitor cells (EPCs) following tumor necrosis factor-α (TNF-α) stimulation …

[HTML][HTML] Resveratrol alleviates lysophosphatidylcholine-induced damage and inflammation in vascular endothelial cells

J Chen, X Cao, Y Cui, G Zeng… - Molecular Medicine …, 2018 - spandidos-publications.com
The role of resveratrol (trans-3, 5, 4'-trihydroxystilbene; RES) in lysophosphatidylcholine
(LPC)‑induced injury and inflammation in endothelial cells (regarded as an early event in …

[HTML][HTML] Resveratrol distinctively modulates the inflammatory profiles of immune and endothelial cells

J Schwager, N Richard, F Widmer… - BMC Complementary and …, 2017 - Springer
Background The phenolic substance resveratrol (RES) is a plant metabolite known to
modulate numerous physiological functions and to exert beneficial effects as a cancer …

[HTML][HTML] Resveratrol attenuates angiotensin II-induced interleukin-6 expression and perivascular fibrosis

K Inanaga, T Ichiki, H Matsuura, R Miyazaki… - Hypertension …, 2009 - nature.com
Recent studies have shown that resveratrol (3, 5, 4′-trihydroxystilbene), a polyphenolic
compound found in grapes and red wine, has various beneficial effects on cardiovascular …

Resveratrol suppresses IL-6-induced ICAM-1 gene expression in endothelial cells: effects on the inhibition of STAT3 phosphorylation

BS Wung, MC Hsu, CC Wu, CW Hsieh - Life Sciences, 2005 - Elsevier
Resveratrol, a polyphenolic phytoaxelin present in red wine, has been suggested to protect
against atherosclerosis and cardiovascular disease because of its antioxidant effects …

Resveratrol improves TNF-α-induced endothelial dysfunction in a coculture model of a Caco-2 with an endothelial cell line

IM Toaldo, J Van Camp, GB Gonzales… - The Journal of nutritional …, 2016 - Elsevier
The bioactivity of trans-resveratrol (RSV), an important wine polyphenol, and of its
metabolites was investigated in a more relevant setup comprising an in vitro coculture cell …