High-risk HPV-positive and-negative high-grade cervical dysplasia: Analysis of 5-year outcomes

G Bogani, F Sopracordevole, V Di Donato… - Gynecologic …, 2021 - Elsevier
Objective To evaluate the outcomes of high-risk (HR) HPV-positive and-negative women
affected by high-grade cervical dysplasia. Methods This is a retrospective multi-institutional …

Risk of high‐grade precancerous lesions and invasive cancers in high‐risk HPV‐positive women with normal cervix or CIN 1 at baseline—A population‐based cohort …

S Mittal, P Basu, R Muwonge… - … journal of cancer, 2017 - Wiley Online Library
Infection with high‐risk human papillomavirus (HR‐HPV) is transient and clears on its own in
majority of the women. Only a few women who have persistent infection may finally develop …

Evidence for frequent regression of cervical intraepithelial neoplasia–grade 2

PE Castle, M Schiffman, CM Wheeler… - Obstetrics & …, 2009 - journals.lww.com
OBJECTIVE: To estimate the fraction of cervical intraepithelial neoplasia 2 (CIN 2) that might
regress if untreated using data from the Atypical Squamous Cells of Undetermined …

Spontaneous regression of high-grade cervical dysplasia: effects of human papillomavirus type and HLA phenotype

CL Trimble, S Piantadosi, P Gravitt, B Ronnett… - Clinical cancer …, 2005 - AACR
Purpose: Persistent infection with oncogenic human papillomaviruses (HPV) plays a central
etiologic role in the development of squamous carcinomas of the cervix and their precursor …

[HTML][HTML] Age-specific predictors of cervical dysplasia recurrence after primary conization: analysis of 3,212 women

G Bogani, C Pinelli, V Chiappa, F Martinelli… - Journal of …, 2020 - ncbi.nlm.nih.gov
Objective This study aimed to identify predictors of recurrence/persistence of cervical
intraepithelial neoplasia grade 2+(CIN2+) lesion (r-CIN2+) after primary conization. Methods …

Multiple high risk HPV infections are common in cervical neoplasia and young women in a cervical screening population

KS Cuschieri, HA Cubie, MW Whitley… - Journal of clinical …, 2004 - jcp.bmj.com
Aims: If human papillomavirus (HPV) testing is to be included within cervical screening
programmes, the importance of multiple HPV infections in cervical neoplasia needs to be …

Human papillomavirus infection determines prognosis in cervical cancer

J Lei, LS Arroyo-Mühr, C Lagheden… - Journal of Clinical …, 2022 - ascopubs.org
PURPOSE Detection of human papillomavirus (HPV) by polymerase chain reaction in
invasive cervical cancer is strongly associated with prognosis but previous studies have not …

Persistence and load of high‐risk HPV are predictors for development of high‐grade cervical lesions: a longitudinal French cohort study

V Dalstein, D Riethmuller, JL Prétet… - … journal of cancer, 2003 - Wiley Online Library
Oncogenic HPV types are the major cause of worldwide cervical cancer, but only a small
proportion of infected women will develop high‐grade cervical intraepithelial neoplasia or …

[HTML][HTML] Age-specific HPV type distribution in high-grade cervical disease in screened and unvaccinated women

K Aro, P Nieminen, K Louvanto, M Jakobsson… - Gynecologic …, 2019 - Elsevier
Background and aim Age-specific type-distribution of high-risk human papillomavirus
(hrHPV) in cervical precancerous lesions is subject to change in the HPV vaccination era …

Outcomes of high-grade cervical dysplasia with positive margins and HPV persistence after cervical conization

A Giannini, V Di Donato, F Sopracordevole, A Ciavattini… - Vaccines, 2023 - mdpi.com
The objective of this work is to assess the 5-year outcomes of patients undergoing
conization for high-grade cervical lesions that simultaneously present as risk factors in the …