The serotonin 5-HT7 receptors: two decades of research

E Gellynck, K Heyninck, KW Andressen… - Experimental brain …, 2013 - Springer
Like most neurotransmitters, serotonin possesses a simple structure. However, the
pharmacological consequences are more complex and diverse. Serotonin is involved in …

Irving Page Lecture: 5-HT2A serotonin receptor biology: Interacting proteins, kinases and paradoxical regulation

BL Roth - Neuropharmacology, 2011 - Elsevier
5-hydroxytryptamine2A (5-HT2A) serotonin receptors are important pharmacological targets
for a large number of central nervous system and peripheral serotonergic medications. In …

Serotonin7 receptors (5-HT7Rs) and their ligands

M Leopoldo - Current medicinal chemistry, 2004 - ingentaconnect.com
Serotonin (5-HT) is involved in various physiological and pathological processes by
interaction with 14 distinct receptor subtypes, grouped in seven classes of receptors (5-HT 1 …

Higher-End Serotonin Receptors:  5-HT5, 5-HT6, and 5-HT7

RA Glennon - Journal of medicinal chemistry, 2003 - ACS Publications
Serotonin (5-hydroxytryptamine, 5-HT; 1) is a major neurotransmitter that is believed to
produce many of its effects via interaction at seven populations of 5-HT receptors, 5-HT1 to 5 …

[图书][B] The serotonin receptors: from molecular pharmacology to human therapeutics

BL Roth - 2008 - books.google.com
A comprehensive, state-of-the-art review of our current understanding of the molecular and
structural biology of 5-HT receptors and their potential use for drug discovery. The authors …

Molecular, pharmacological and functional diversity of 5-HT receptors

D Hoyer, JP Hannon, GR Martin - Pharmacology Biochemistry and …, 2002 - Elsevier
Serotonin (5-hydroxytryptamine, 5-HT) is probably unique among the monoamines in that its
effects are subserved by as many as 13 distinct heptahelical, G-protein-coupled receptors …

Serotonin 5-HT3 receptors in the central nervous system

P Chameau, JA van Hooft - Cell and tissue research, 2006 - Springer
The 5-HT 3 receptor is a ligand-gated ion channel activated by serotonin (5-HT). Although
originally identified in the peripheral nervous system, the 5-HT 3 receptor is also …

Cloning, Characterization, and Chromosomal Localization of a Human 5‐HT6 Serotonin Receptor

R Kohen, MA Metcalf, N Khan, T Druck… - Journal of …, 1996 - Wiley Online Library
We describe the cloning and characterization of a human 5‐HT6 serotonin receptor. The
open reading frame is interrupted by two introns in positions corresponding to the third …

[HTML][HTML] The serotonin-6 receptor as a novel therapeutic target

HM Yun, H Rhim - Experimental neurobiology, 2011 - ncbi.nlm.nih.gov
Abstract Serotonin (5-hydroxytryptamine, 5-HT) is an important neurotransmitter that is found
in both the central and peripheral nervous systems. 5-HT mediates its diverse physiological …

Characterization of the novel human serotonin receptor subunits 5-HT3C, 5-HT3D, and 5-HT3E

B Niesler, J Walstab, S Combrink, D Moeller… - Molecular …, 2007 - ASPET
Within the family of serotonin receptors, the 5-hydroxytryptamine-3 (5-HT3) receptor is the
only ligand-gated ion channel. It is composed of five subunits, of which the 5-HT3A and 5 …