Glia alterations in the anterior cingulate cortex (ACC) and dorsolateral prefrontal cortex
(DLPFC) have been postulated to play an important role in the pathophysiology of …

Stress-induced disturbances of brain homeostasis and neuroinflammation have been
implicated in the pathophysiology of mood disorders. In major depressive disorder (MDD) …

Few studies report the microglia involvement in the pathogenesis of panic disorder (PD),
although the crucial role of microglia in other neuropsychiatric diseases is being …

Mood disorders have multiple phenotypes and complex underlying biological mechanisms
and, as such, there are no effective therapeutic strategies. A review of recent work on the …

Major depressive disorder (MDD) affects more than cognition, having a temporal
relationship with neuroinflammatory pathways of Parkinson's disease (PD). Although this …

Background Anhedonia, as the core endophenotype of major depressive disorder (MDD), is
closely related to poor prognosis, but the mechanism of this feature remains to be …

Background Microglia have been implicated in the pathophysiology of major depressive
disorder (MDD), but information on biological mechanisms is limited. Therefore, we …

Major depressive disorder (MDD) is a prevalent psychiatric disorder, and exposure to stress
is a robust risk factor for MDD. Clinical data and rodent models have indicated the negative …

Recent studies have suggested that cortical astroglia play an important role in depressive-
like behaviors. Potential astroglial contributions have been proposed based on their known …

Background Motor symptoms are well-characterized in Parkinson's disease (PD). However,
non-motor symptoms, such as depression, are commonly observed and can appear up to 10 …