Pemphigus is a complex dermatologic autoimmune bullous disease whose pathogenic
mechanism is not fully understood. Anti-desmoglein-1 (Dsg1) and anti-Dsg3 autoantibodies …

The loss of balance between regulatory T (Treg) and T helper 17 (Th17) causes loss of
tolerance against desmoglein (Dsg)-3 leading to pemphigus vulgaris (PV), an autoimmune …

Th17 cells play crucial roles in the pathogenesis of autoimmune diseases. We previously
reported that Th17 cells are recruited to the lesional skin in pemphigus vulgaris (PV) and …

Pemphigus is an autoimmune disease in which IgG auto-antibodies (auto-ab) against the
desmosomal cadherins desmoglein (Dsg) 3 and Dsg1 cause loss of epidermal keratinocyte …

Pemphigus vulgaris (PV) is an autoimmune disease characterized by the presence of IgG
autoantibodies against desmoglein-3. Despite the variety of findings, the chemokine and …

Pemphigus vulgaris is an autoimmune disease, in which the role of Th17 cytokines needs to
be further explored. This study was performed to assess serum levels of three interleukins …

T helper 17 (Th17) plays a pivotal role in the pathogenesis of autoimmune diseases, such as
autoimmune encephalitis and inflammatory bowel diseases, in which Th1 previously were …

Background Although regulatory T cells (Tregs) are affected in several autoimmune skin
diseases, only two studies have been performed in patients with bullous pemphigoid (BP) …

Background TH 2 cells were thought to be a pivotal factor for initiation of the autoimmune
blistering disease pemphigus. However, the role of other T-cell subsets in pemphigus …

Pemphigus vulgaris (PV) is an autoimmune bullous skin disease where tolerance to the
desmosomal protein desmoglein 3 (Dsg3), and perhaps additional epidermal targets, is lost …