CGRP as a neuropeptide in migraine: lessons from mice
AF Russo - British journal of clinical pharmacology, 2015 - Wiley Online Library
Migraine is a neurological disorder that is far more than just a bad headache. A hallmark of
migraine is altered sensory perception. A likely contributor to this altered perception is the …
migraine is altered sensory perception. A likely contributor to this altered perception is the …
Calcitonin gene-related peptide (CGRP): a new target for migraine
AF Russo - Annual review of pharmacology and toxicology, 2015 - annualreviews.org
Migraine is a neurological disorder that manifests as a debilitating headache associated
with altered sensory perception. The neuropeptide calcitonin gene-related peptide (CGRP) …
with altered sensory perception. The neuropeptide calcitonin gene-related peptide (CGRP) …
Induction of migraine-like photophobic behavior in mice by both peripheral and central CGRP mechanisms
BN Mason, EA Kaiser, A Kuburas… - Journal of …, 2017 - Soc Neuroscience
The neuropeptide calcitonin gene-related peptide (CGRP) is a key player in migraine.
Although migraine can be treated using CGRP antagonists that act peripherally, the relevant …
Although migraine can be treated using CGRP antagonists that act peripherally, the relevant …
[HTML][HTML] A potential preclinical migraine model: CGRP-sensitized mice
The neuropeptide calcitonin gene-related peptide (CGRP) plays a key role in migraine.
However, a major challenge for studying CGRP actions is the lack of animal models for …
However, a major challenge for studying CGRP actions is the lack of animal models for …
CGRP in animal models of migraine
AS Wattiez, M Wang, AF Russo - Calcitonin Gene-Related Peptide (CGRP …, 2019 - Springer
With the approval of calcitonin gene-related peptide (CGRP) and CGRP receptor
monoclonal antibodies by the Federal Drug Administration, a new era in the treatment of …
monoclonal antibodies by the Federal Drug Administration, a new era in the treatment of …
CGRP and migraine: could PACAP play a role too?
Migraine is a debilitating neurological disorder that affects about 12% of the population. In
the past decade, the role of the neuropeptide calcitonin gene-related peptide (CGRP) in …
the past decade, the role of the neuropeptide calcitonin gene-related peptide (CGRP) in …
CGRP in human models of migraine
Over the past three decades, calcitonin gene-related peptide (CGRP) has emerged as a key
molecule. Provocation experiments have demonstrated that intravenous CGRP infusion …
molecule. Provocation experiments have demonstrated that intravenous CGRP infusion …
Pain pharmacology in migraine: focus on CGRP and CGRP receptors
Over the last 100 years, the discovery of new analgesics has been a complex and difficult
task. However, remarkable progress in the identification of novel molecular targets relevant …
task. However, remarkable progress in the identification of novel molecular targets relevant …
Calcitonin gene-related peptide (CGRP): role in migraine pathophysiology and therapeutic targeting
Introduction: The neuropeptide calcitonin gene-related peptide (CGRP) is recognized as a
critical player in migraine pathophysiology. Excitement has grown regarding CGRP because …
critical player in migraine pathophysiology. Excitement has grown regarding CGRP because …
CGRP antagonists: unravelling the role of CGRP in migraine
H Doods, K Arndt, K Rudolf, S Just - Trends in pharmacological sciences, 2007 - cell.com
Migraine is a complex, debilitating neurovascular disorder. Although knowledge on the main
molecular players is still incomplete, recent preclinical and clinical findings indicate that …
molecular players is still incomplete, recent preclinical and clinical findings indicate that …