Synthetic nanoparticles for delivery of radioisotopes and radiosensitizers in cancer therapy

J Zhao, M Zhou, C Li - Cancer nanotechnology, 2016 - Springer
Radiotherapy has been, and will continue to be, a critical modality to treat cancer. Since the
discovery of radiation-induced cytotoxicity in the late 19th century, both external and internal …

Nanoparticles for radiooncology: Mission, vision, challenges

LA Kunz-Schughart, A Dubrovska, C Peitzsch, A Ewe… - Biomaterials, 2017 - Elsevier
Cancer is one of the leading non-communicable diseases with highest mortality rates
worldwide. About half of all cancer patients receive radiation treatment in the course of their …

Nanoparticles for targeted cancer radiotherapy

RM Pallares, RJ Abergel - Nano Research, 2020 - Springer
Radiotherapy, where ionizing radiation is locally delivered either through an external beam
or by surgically implanting radionuclide-based seeds in the tumor, is one of the gold …

Radiosensitization and nanoparticles

T Paunesku, S Gutiontov, K Brown… - … -Based Precision Tools …, 2015 - Springer
Nanomaterials have been shown to have physical and chemical properties that have
opened new avenues for cancer diagnosis and therapy. Nanoconstructs that enhance …

[HTML][HTML] Nanoparticle-based radiosensitization strategies for improving radiation therapy

H Shen, H Huang, Z Jiang - Frontiers in Pharmacology, 2023 - frontiersin.org
Radiotherapy remains the mainstay treatment for a variety of cancer forms. However, the
therapeutic efficiency of radiation is significantly limited by several aspects, including high …

Advances of nanomedicine in radiotherapy

W Liu, B Chen, H Zheng, Y Xing, G Chen, P Zhou… - Pharmaceutics, 2021 - mdpi.com
Radiotherapy (RT) remains one of the current main treatment strategies for many types of
cancer. However, how to improve RT efficiency while reducing its side effects is still a large …

Delivery of therapeutic radioisotopes using nanoparticle platforms: potential benefit in systemic radiation therapy

L Zhang, H Chen, L Wang, T Liu, J Yeh… - Nanotechnology …, 2010 - Taylor & Francis
Radiation therapy is an effective cancer treatment option in conjunction with chemotherapy
and surgery. Emerging individualized internal and systemic radiation treatment promises …

Chemoradiotherapy of human tumors: novel approaches from nanomedicine

M Edward Werner, M Bonner Foote… - Current …, 2012 - ingentaconnect.com
Chemoradiotherapy is an important treatment paradigm in oncology and is part of the
curative treatment for many solid cancers, such as lung, pancreatic and cervical cancers …

Mechanisms of nanoparticle radiosensitization

I Kempson - Wiley Interdisciplinary Reviews: Nanomedicine …, 2021 - Wiley Online Library
Metal‐based nanoparticles applied to potentiating the effects of radiotherapy have drawn
significant attention from the research community and are now available clinically. By …

Delivery of nanoparticle-based radiosensitizers for radiotherapy applications

F Boateng, W Ngwa - International journal of molecular sciences, 2019 - mdpi.com
Nanoparticle-based radiosensitization of cancerous cells is evolving as a favorable modality
for enhancing radiotherapeutic ratio, and as an effective tool for increasing the outcome of …