Evaluation of mefenamic acid mutual prodrugs
Mutual prodrugs consisting of mefenamic acid with menthol and thymol have been
synthesized as a gastrosparing NSAIDs, devoid of ulcerogenic side effects. The structures of …
synthesized as a gastrosparing NSAIDs, devoid of ulcerogenic side effects. The structures of …
[PDF][PDF] Synthesis of prodrugs of mefenamic acid and their in vivo evaluation
DP Kemisetti, S Manda, J Aukunuru… - International Journal of …, 2014 - academia.edu
Objective: The purpose of the study was to synthesize prodrugs of mefenamic acid, to be
used as Anti inflammatory drug with fewer adverse effects. Methods: The drug was …
used as Anti inflammatory drug with fewer adverse effects. Methods: The drug was …
[PDF][PDF] Synthesis, kinetics and pharmacological evaluation of mefenamic acid mutual prodrug
A novel mutual prodrug (MA-P) consisting of mefenamic acid (MA) and paracetamol (P) has
been synthesized as a gastrosparing NSAID, devoid of ulcerogenic side effects. The …
been synthesized as a gastrosparing NSAID, devoid of ulcerogenic side effects. The …
Synthesis and pharmacological evaluation of mutual prodrugs of aceclofenac with quercetin, vanillin and l-tryptophan as gastrosparing NSAIDS
Synthesis, physicochemical characterization and pharmacological evaluation of mutual
prodrugs of aceclofenac with quercetin, vanillin and l-tryptophan have been attempted to …
prodrugs of aceclofenac with quercetin, vanillin and l-tryptophan have been attempted to …
[PDF][PDF] Synthesis, spectral studies, hydrolysis kinetics and pharmacodynamic profile of mefenamic acid prodrugs
BV Dhokchawle, MD Kamble, SJ Tauro… - Der Pharma …, 2014 - academia.edu
Prodrugs of mefenamic acid with natural compounds eugenol and vanillin have been
synthesized by dicyclohexylcarbodimide coupling method. Purified synthesized ester …
synthesized by dicyclohexylcarbodimide coupling method. Purified synthesized ester …
Mefenamic acid prodrugs and codrugs-two decades of development
A Abu-Jaish, G Mecca, S Jumaa, A Thawabteh - 2015 - dspace.alquds.edu
Abstract prodrugs are bioreversible derivatives of drug molecules that undergo
intermolecular or intramolecular reactions by enzymatic or chemical biotransformation in the …
intermolecular or intramolecular reactions by enzymatic or chemical biotransformation in the …
Synthesis, biological evaluation and pharmacokinetic studies of mefenamic acid-N-hydroxymethylsuccinimide ester prodrug as safer NSAID
Background: Non steroidal anti-inflammatory drugs are the most widely prescribed drugs to
manage pain and inflammatory conditions, but their long term use is associated with …
manage pain and inflammatory conditions, but their long term use is associated with …
Synthesis and biological evaluation of mutual prodrugs of carboxylic group containing some non-steroidal anti-inflammatory drugs and propyphenazone
Background: The use of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) is not up to its
potential because of their gastrointestinal side effects. Significant attention has been focused …
potential because of their gastrointestinal side effects. Significant attention has been focused …
Tyrosine and glycine derivatives as potential prodrugs: design, synthesis, and pharmacological evaluation of amide derivatives of mefenamic acid
A Rasheed, CK Ashok Kumar - Journal of enzyme inhibition and …, 2010 - Taylor & Francis
This study deals with the synthesis, pharmacological activity, and kinetic studies of
mefenamic acid (MA) prodrugs of tyrosine and glycine. The synthesis involved a series of …
mefenamic acid (MA) prodrugs of tyrosine and glycine. The synthesis involved a series of …
Formulation and evaluation of suspensions: Mefenamic acid prodrugs.
K Shah, SK Shrivastava… - Pakistan journal of …, 2014 - search.ebscohost.com
Gastrosparing novel prodrugs (MAM and MAT) synthesized consisted of mefenamic acid
(MA) with menthol (M) and thymol (T). Structural characterizations of synthesized esters …
(MA) with menthol (M) and thymol (T). Structural characterizations of synthesized esters …