Phenotypic heterogeneity and cellular origins of T cell malignancies

MF Greaves, J Rao, G Hariri, W Verbi, D Catovsky… - Leukemia Research, 1981 - Elsevier
Untreated T cell malignancies (82) and T leukaemic cell lines (13) have been analysed by
fluorescence microscopy and flow cytometry (FACS) using a series of monoclonal …

The human T-cell leukemias: clinical, cytomorphologic, immunophenotypic, and genotypic characteristics

DM Knowles II - Human pathology, 1986 - Elsevier
The distribution of the conventional lymphoid cell markers on T lymphocytes and the
principal panels of monoclonal antibodies used to recognize distinctive T-lymphocyte …

Mature T-cell leukemias and leukemia/lymphoma syndromes: review of our experience in 175 cases

E Matutes, D Catovsky - Leukemia & Lymphoma, 1991 - Taylor & Francis
The T-lymphoproliferative disorders are an heterogeneous group of diseases which result
from the clonal expansion of T cells at various stages of differentiation. Two main groups of …

Cytogenetic and immunophenotypic analysis of cell lines established from patients with T cell leukemia/lymphoma

SD Smith, R Morgan, MP Link, P McFall, F Hecht - 1986 - ashpublications.org
Cell lines were established from five patients with T cell malignancies. Two patients had T
cell lymphoblastic lymphoma (T-LL), whereas three patients had T cell acute lymphoblastic …

Monoclonal antibody characterization of surface antigens in childhood T-cell lymphoid malignancies

M Roper, WM Crist, R Metzgar, AH Ragab, S Smith… - 1983 - ashpublications.org
Although childhood T-cell acute lymphocytic leukemia (T-ALL) and T-cell non-Hodgkin's
lymphoma (T-NHL) have certain clinical features in common, T-ALL carries a notably poorer …

Heterogeneity of T-cell lymphoblastic malignancies

LM Nadler, EL Reinherz, HJ Weinstein, CJ D'Orsi… - 1980 - ashpublications.org
To determine the T-cell lineage of the malignant lymphoblast in lymphoblastic lymphoma,
tumor cells from nine patients were phenotyped employing a T-cell subset specific …

Heterogeneity of T-acute lymphoblastic leukemia (T-ALL) cell lines: suggestion for classification by immunophenotype and T-cell receptor studies

R Burger, TE Hansen-Hagge, HG Drexler… - Leukemia research, 1999 - Elsevier
Hematopoietic cell lines are often used as representatives for a certain cell differentiation
lineage and stage, particularly in immunological and hematological studies. Acute …

Candidate counterparts of Sézary cells and adult T-cell lymphoma-leukaemia cells in normal peripheral blood: an ultrastructural study with the immunogold method …

E Matutes, D Robinson, M O'Brien, BF Haynes… - Leukemia Research, 1983 - Elsevier
The ultrastructural and immunologic features of normal convoluted T-lymphocytes were
studied with a panel of monoclonal antibodies and the immunogold technique and these …

Derivation of human T-cell leukemias

EL Reinherz, SF Schlossman - Cancer research, 1981 - AACR
Cell surface antigenic changes occur during the stages of T-cell ontogeny in several animal
model systems. In the present study, multiple monoclonal antibodies were developed to …

Discrete stages of human intrathymic differentiation: analysis of normal thymocytes and leukemic lymphoblasts of T-cell lineage

EL Reinherz, PC Kung, G Goldstein… - Proceedings of the …, 1980 - National Acad Sciences
A series of monoclonal antibodies was used to define three discrete stages of human
intrathymic T-cell differentiation. The earliest stage was confined to< 10% of thymocytes …