Cocaine-induced plasticity in the cerebellum of sensitised mice
D Vazquez-Sanroman, M Carbo-Gas, K Leto… - …, 2015 - Springer
Rationale Prior research has accumulated a substantial amount of evidence on the ability of
cocaine to produce short-and long-lasting molecular and structural plasticity in the …
cocaine to produce short-and long-lasting molecular and structural plasticity in the …
The addicted brain: understanding the neurophysiological mechanisms of addictive disorders
The consumption of chemical substances that produce transient feelings of euphoria or
pleasure and the development of dependence on those substances by a subset of …
pleasure and the development of dependence on those substances by a subset of …
The cerebellum on cocaine: plasticity and metaplasticity
D Vazquez‐Sanroman, K Leto… - Addiction …, 2015 - Wiley Online Library
Despite the fact that several data have supported the involvement of the cerebellum in the
functional alterations observed after prolonged cocaine use, this brain structure has been …
functional alterations observed after prolonged cocaine use, this brain structure has been …
Nicotine-induced structural plasticity in mesencephalic dopaminergic neurons is mediated by dopamine D3 receptors and Akt-mTORC1 signaling
Although long-term exposure to nicotine is highly addictive, one beneficial consequence of
chronic tobacco use is a reduced risk for Parkinson's disease. Of interest, these effects both …
chronic tobacco use is a reduced risk for Parkinson's disease. Of interest, these effects both …
Plasticity of addiction: a mesolimbic dopamine short-circuit?
JL Niehaus, ND Cruz-Bermúdez… - American Journal on …, 2009 - Taylor & Francis
The development of drug addiction progresses along a continuum from acute drug use to
compulsive use and drug seeking behavior. Many researchers have focused on identifying …
compulsive use and drug seeking behavior. Many researchers have focused on identifying …
Dopamine in drug abuse and addiction: results from imaging studies and treatment implications
ND Volkow, JS Fowler, GJ Wang, JM Swanson - Molecular psychiatry, 2004 - nature.com
The involvement of dopamine in drug reinforcement is well recognized but its role in drug
addiction is much less clear. Imaging studies have shown that the reinforcing effects of drugs …
addiction is much less clear. Imaging studies have shown that the reinforcing effects of drugs …
Cocaine and amphetamine-like psychostimulants: neurocircuitry and glutamate neuroplasticity
PW Kalivas - Dialogues in clinical neuroscience, 2007 - Taylor & Francis
Although the pharmacology of amphetamine-like psychostimulants at dopamine transporters
is well understood, addiction to this class of drugs has proven difficult to deal with. The …
is well understood, addiction to this class of drugs has proven difficult to deal with. The …
Dopamine triggers heterosynaptic plasticity
M Ishikawa, M Otaka, YH Huang… - Journal of …, 2013 - Soc Neuroscience
As a classic neuromodulator, dopamine has long been thought to modulate, rather than
trigger, synaptic plasticity. In contrast, our present results demonstrate that within the parallel …
trigger, synaptic plasticity. In contrast, our present results demonstrate that within the parallel …
Determination of circuit-specific morphological adaptations in ventral tegmental area dopamine neurons by chronic morphine
SC Simmons, K Wheeler, MS Mazei-Robison - Molecular brain, 2019 - Springer
Chronic opiate exposure induces neuroadaptations in the mesocorticolimbic system
including ventral tegmental area (VTA) dopamine (DA) neurons, whose soma size is …
including ventral tegmental area (VTA) dopamine (DA) neurons, whose soma size is …
Glial-neuronal ensembles: partners in drug addiction-associated synaptic plasticity
JL Cadet, V Bisagno - Frontiers in pharmacology, 2014 - frontiersin.org
Drug addiction is manifested by a compulsive drive to take licit or illicit substances despite
repeated severe adverse consequences (Volkow et al., 2012). Addiction is also …
repeated severe adverse consequences (Volkow et al., 2012). Addiction is also …