The previous in vivo study revealed the carrier-mediated transport of riboflavin (vitamin B 2)
across the blood-retinal barrier (BRB). In the present study, the blood-to-retina supply of …

Riboflavin (vitamin B 2) supply to the retina across the inner blood-retinal barrier (BRB) was
investigated. In rats, the apparent influx permeability clearance of [3 H] riboflavin (62.8 …

Drug delivery to the retina is a challenging task owing to its complex physiology and
presence of the blood-retinal barrier (BRB), which regulates the permeation of substances …

Riboflavin (vitamin B2) plays a role in various biochemical oxidation-reduction reactions.
Flavin mononucleotide (FMN) and FAD, the biologically active forms, are made from …

Purpose: To investigate the functional expression of a carrier-mediated transport mechanism
for riboflavin (vitamin B 2) across cultured rabbit primary corneal epithelial cells (rPCECs) …

The retention and cellular internalization of drug delivery systems and theranostics for
cancer therapy can be improved by targeting molecules. Since an increased uptake of …

The blood-to-retina supply of cyanocobalamin (vitamin B12) across the blood–retinal barrier
(BRB) was investigated by synthesizing a fluorescence-labeled cyanocobalamin (Cy5 …

Introduction: The blood-retinal barrier (BRB) is the barrier separating the blood and neural
retina, and transport systems for low-weight molecules at the BRB are expected to be useful …

Riboflavin is an important water soluble vitamin (B2) required for metabolic reactions,
normal cellular growth, differentiation and function. Mammalian brain cells cannot …

Background: the SLC52A2 gene encodes for the riboflavin transporter 2 (RFVT2). This
transporter is ubiquitously expressed. It mediates the transport of Riboflavin across cell …