Cell-based therapies for coronavirus disease 2019: proper clinical investigations are essential

M Khoury, PRM Rocco, DG Phinney, M Krampera… - Cytotherapy, 2020 - Elsevier
The serious consequences of the global coronavirus disease 2019 (COVID-19) pandemic
have prompted a rapid global response to develop effective therapies that can lessen …

Cell-based therapy to reduce mortality from COVID-19: Systematic review and meta-analysis of human studies on acute respiratory distress syndrome

W Qu, Z Wang, JM Hare, G Bu… - Stem Cells …, 2020 - academic.oup.com
Severe cases of COVID-19 infection, often leading to death, have been associated with
variants of acute respiratory distress syndrome (ARDS). Cell therapy with mesenchymal …

Current status of cell-based therapies for COVID-19: evidence from mesenchymal stromal cells in sepsis and ARDS

Z Xu, Y Huang, J Zhou, X Deng, W He, X Liu… - Frontiers in …, 2021 - frontiersin.org
The severe respiratory consequences of the coronavirus disease 2019 (COVID-19)
pandemic have prompted the urgent need for novel therapies. Cell-based therapies …

Potential cell-based and cell-free therapy for patients with COVID-19

MI Tan, NM Alfarafisa, P Septiani, A Barlian… - Cells, 2022 - mdpi.com
Since it was first reported, the novel coronavirus disease 2019 (COVID-19) remains an
unresolved puzzle for biomedical researchers in different fields. Various treatments, drugs …

Current status of cell-based therapies for respiratory virus infections: applicability to COVID-19

M Khoury, J Cuenca, FF Cruz… - European respiratory …, 2020 - Eur Respiratory Soc
The severe respiratory consequences of the coronavirus disease 2019 (COVID-19)
pandemic have prompted urgent need for novel therapies. Cell-based approaches, primarily …

The rationale of using mesenchymal stem cells in patients with COVID-19-related acute respiratory distress syndrome: What to expect

A Can, H Coskun - Stem Cells Translational Medicine, 2020 - academic.oup.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-caused coronavirus
disease 2019 (COVID-19) pandemic has become a global health crisis with an extremely …

Efficacy of MSC in patients with severe COVID-19: analysis of the literature and a case study

M Grumet, J Sherman, BS Dorf - Stem cells translational …, 2022 - academic.oup.com
Patients with severe COVID-19 experience cytokine storm, an uncontrolled upregulation of
pro-inflammatory cytokines, which if unresolved leads to acute respiratory distress syndrome …

Efficacy and safety of MSC cell therapies for hospitalized patients with COVID-19: a systematic review and meta-analysis

W Qu, Z Wang, E Engelberg-Cook… - Stem cells …, 2022 - academic.oup.com
MSC (aka mesenchymal stem cell or medicinal signaling cell) cell therapies show promise
in decreasing mortality in acute respiratory distress syndrome (ARDS) and suggest benefits …

The coronavirus pandemic: a pitfall or a fast track for validating cell therapy products?

M Khoury, L Ikonomou, M Dominici… - Stem Cells and …, 2021 - liebertpub.com
The global COVID-19 pandemic has prompted urgent need for potential therapies for severe
respiratory consequences resulting from coronavirus infection. New therapeutic agents that …

Therapeutic mechanisms of mesenchymal stem cells in acute respiratory distress syndrome reveal potentials for Covid-19 treatment

W Wang, W Lei, L Jiang, S Gao, S Hu, ZG Zhao… - Journal of translational …, 2021 - Springer
The mortality rate of critically ill patients with acute respiratory distress syndrome (ARDS) is
30.9% to 46.1%. The emergence of the coronavirus disease 2019 (Covid-19) has become a …