N‑terminal truncated peroxisome proliferator‑activated receptor‑γ coactivator‑1α alleviates phenylephrine‑induced mitochondrial dysfunction and decreases lipid …
Z Liu, J Hua, W Cai, Q Zhan, W Lai… - Molecular …, 2018 - spandidos-publications.com
N‑terminal truncated peroxisome proliferator‑activated receptor‑γ coactivator‑1α (NT‑PGC‑
1α) is an alternative splice variant of PGC‑1α. NT‑PGC‑1α exhibits stronger anti‑obesity …
1α) is an alternative splice variant of PGC‑1α. NT‑PGC‑1α exhibits stronger anti‑obesity …
Peroxisome proliferator-activated receptor δ (PPARδ) activation protects H9c2 cardiomyoblasts from oxidative stress-induced apoptosis
M Pesant, S Sueur, P Dutartre… - Cardiovascular …, 2006 - academic.oup.com
Objective: Activation of peroxisome proliferator-activated receptor α (PPARα) and PPARγ
plays beneficial roles in cardiovascular disorders such as atherosclerosis and heart …
plays beneficial roles in cardiovascular disorders such as atherosclerosis and heart …
[PDF][PDF] Down-regulation of the expression of angiotensin II type 1 receptor in neonatal rat cardiac fibroblast by activation of PPARgamma signal pathway
SM Zhao, LH Shen, HW Li, L Wang, H Chen, YL Wang… - Chin J Physiol, 2008 - cps.org.tw
Peroxisome proliferator-activated receptor-gamma (PPARγ) is one of the hormone nuclear
receptors. Recent data have shown that activation of PPARγ signal pathway has many …
receptors. Recent data have shown that activation of PPARγ signal pathway has many …
[PDF][PDF] Atorvastatin attenuating down-regulation of peroxisome proliferator-activated receptor gamma in preventing cardiac hypertrophy of rats in vitro and in vivo
P Ye, L Sheng, C Zhang, Y Liu - J Pharm Pharm Sci, 2006 - ualberta.ca
Purpose. To investigate whether the role of atorvastatin in suppression of cardiac
hypertrophy is potentially associated with the change of peroxisome proliferator-activated …
hypertrophy is potentially associated with the change of peroxisome proliferator-activated …
The peroxisome proliferator-activated receptor-α (PPAR-α) agonist, AVE8134, attenuates the progression of heart failure and increases survival in rats
W Linz, P Wohlfart, M Baader, K Breitschopf… - Acta Pharmacologica …, 2009 - nature.com
Aim: To investigate the efficacy of the peroxisome proliferator-activated receptor-α (PPARα)
agonist, AVE8134, in cellular and experimental models of cardiac dysfunction and heart …
agonist, AVE8134, in cellular and experimental models of cardiac dysfunction and heart …
Modulation of fatty acid metabolism is involved in the alleviation of isoproterenol-induced rat heart failure by fenofibrate
P Li, S Luo, C Pan, X Cheng - Molecular Medicine …, 2015 - spandidos-publications.com
Heart failure is a disease predominantly caused by an energy metabolic disorder in
cardiomyocytes. The present study investigated the inhibitory effects of fenofibrate (FF) on …
cardiomyocytes. The present study investigated the inhibitory effects of fenofibrate (FF) on …
Effects of PPARs agonists on cardiac metabolism in littermate and cardiomyocyte-specific PPAR-γ–knockout (CM-PGKO) mice
M Barbieri, C Di Filippo, A Esposito, R Marfella… - PLoS …, 2012 - journals.plos.org
Understanding the molecular regulatory mechanisms controlling for myocardial lipid
metabolism is of critical importance for the development of new therapeutic strategies for …
metabolism is of critical importance for the development of new therapeutic strategies for …
Peroxisome proliferator-activated receptor β stimulation induces rapid cardiac growth and angiogenesis via direct activation of calcineurin
N Wagner, C Jehl-Piétri, P Lopez… - Cardiovascular …, 2009 - academic.oup.com
Aims Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription
factors. PPARβ agonists were suggested as potential drugs for the treatment of metabolic …
factors. PPARβ agonists were suggested as potential drugs for the treatment of metabolic …
Activation of the peroxisome proliferator-activated receptor α protects against myocardial ischaemic injury and improves endothelial vasodilatation
A Tabernero, K Schoonjans, L Jesel, I Carpusca… - BMC …, 2002 - Springer
Background The peroxisome proliferator-activated receptor α (PPARα) plays an important
role in the metabolism of lipoproteins and fatty acids, and seems to protect against the …
role in the metabolism of lipoproteins and fatty acids, and seems to protect against the …
PPAR-alpha activation as a preconditioning-like intervention in rats in vivo confers myocardial protection against acute ischaemia–reperfusion injury: involvement of …
T Ravingerová, S Čarnická… - Canadian journal of …, 2012 - cdnsciencepub.com
Peroxisome proliferator-activated receptors (PPAR) regulate the expression of genes
involved in lipid metabolism, energy production, and inflammation. Their role in ischaemia …
involved in lipid metabolism, energy production, and inflammation. Their role in ischaemia …