Efficacy and safety of oral GnRh antagonists in patients with uterine fibroids: a systematic review

R Niaz, M Saeed, H Khan, MA Ali, A Irshad… - Journal of obstetrics and …, 2022 - Elsevier
Objective This review aimed to assess the efficacy and safety of GnRH antagonists in
patients with symptomatic uterine fibroids. Data Sources A literature search was performed …

Considerations on implementation of the newest treatment for symptomatic uterine fibroids: Oral GnRH antagonists

ME de Lange, A Semmler, TJ Clark… - British journal of …, 2024 - Wiley Online Library
Novel gonadotrophin releasing hormone (GnRH) antagonist treatments have recently been
developed in combination with hormonal add‐back therapy, as an oral treatment option for …

Treatment of symptoms of uterine fibroids with relugolix combination therapy: Efficacy and safety results from the Phase 3 LIBERTY 1 clinical trial

A Al-Hendy, AS Lukes, A Poindexter, R Venturella… - Fertility and …, 2019 - fertstert.org
Objective To evaluate the efficacy and safety of 24 weeks of treatment with the oral GnRH
receptor antagonist, relugolix, in combination with estradiol (E2) and norethindrone acetate …

Add‐back therapy with GnRH analogues for uterine fibroids

RM Moroni, WP Martins, RA Ferriani… - Cochrane Database …, 2015 - cochranelibrary.com
Background Uterine fibroids (also known as leiomyomas) are the most common benign
pelvic tumours among women. They may be asymptomatic, or may be associated with pelvic …

Relugolix for the treatment of uterine fibroids

ML Rocca, AR Palumbo, D Lico… - Expert Opinion on …, 2020 - Taylor & Francis
Introduction Uterine fibroids (UF) are benign tumors common in premenopausal women,
with strong impact on the health-care systems. For many years, surgery represented the only …

GnRH agonists and antagonists in therapy of symptomatic uterine fibroids–current roles and future perspectives

M Ciebiera, OS Madueke-Laveaux… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Uterine fibroids are the most common noncancerous tumors in women of
childbearing age. This review was developed to evaluate the current role of gonadotropin …

[HTML][HTML] Use of oral GnRH antagonists combined therapy in the management of symptomatic uterine fibroids

ADS SArDo, F Ciccarone, L Muzii… - Facts, Views & Vision …, 2023 - ncbi.nlm.nih.gov
Use of oral GnRH antagonists combined therapy in the management of symptomatic uterine
fibroids - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage …

Clinical utility of elagolix as an oral treatment for women with uterine fibroids: a short report on the emerging efficacy data

M Neri, GB Melis, E Giancane, V Vallerino… - … Journal of Women's …, 2019 - Taylor & Francis
Uterine fibroids (UFs) are the most common gynaecological benign disease. Even though
often asymptomatic, UFs can worsen women's health and their quality of life, causing heavy …

Experimental and new investigational drugs for the treatment of uterine fibroids

G Evangelisti, S Ferrero, U Perrone… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction Uterine fibroids, the most prevalent benign tumors among reproductive-age
women, pose treatment challenges that range from surgical interventions to medical …

Current approaches to overcome the side effects of GnRH analogs in the treatment of patients with uterine fibroids

M Ali, M Raslan, M Ciebiera, K Zaręba… - Expert opinion on drug …, 2022 - Taylor & Francis
ABSTRACT Introduction: Uterine fibroids (UFs) are the most prevalent benign neoplastic
threat originating from myometria of reproductive age women, with a profound financial load …