Inflammation and cardiovascular diseases: lessons from seminal clinical trials
L Liberale, F Montecucco, L Schwarz… - Cardiovascular …, 2021 - academic.oup.com
Inflammation has been long regarded as a key contributor to atherosclerosis. Inflammatory
cells and soluble mediators play critical roles throughout arterial plaque development and …
cells and soluble mediators play critical roles throughout arterial plaque development and …
[HTML][HTML] Critical roles of inflammation in atherosclerosis
J Moriya - Journal of cardiology, 2019 - Elsevier
There is accumulating evidence that vascular inflammation plays critical roles in
pathophysiology of atherosclerosis. It is widely accepted that both innate and adaptive …
pathophysiology of atherosclerosis. It is widely accepted that both innate and adaptive …
[HTML][HTML] Inflammation in atherosclerotic cardiovascular disease
PK Shah, D Lecis - F1000Research, 2019 - ncbi.nlm.nih.gov
Atherosclerotic cardiovascular disease is a leading cause of death and morbidity globally.
Over the past several years, arterial inflammation has been implicated in the …
Over the past several years, arterial inflammation has been implicated in the …
[HTML][HTML] Antiinflammatory therapy in clinical care: the CANTOS trial and beyond
Inflammation is a critical pathway in the pathogenesis of atherosclerosis. Previous studies
have shown that plasma levels of high-sensitivity C-reactive protein (hsCRP), a marker of …
have shown that plasma levels of high-sensitivity C-reactive protein (hsCRP), a marker of …
Anti-inflammatory therapies for atherosclerosis
M Bäck, GK Hansson - Nature Reviews Cardiology, 2015 - nature.com
The view of atherosclerosis as an inflammatory disease has emerged from observations of
immune activation and inflammatory signalling in human atherosclerotic lesions, from the …
immune activation and inflammatory signalling in human atherosclerotic lesions, from the …
[HTML][HTML] Inflammation as a therapeutic target in atherosclerosis
MT Nguyen, S Fernando, N Schwarz, JTM Tan… - Journal of clinical …, 2019 - mdpi.com
Atherosclerotic coronary artery disease (CAD) results from build-up of cholesterol-rich
plaques in the walls of the coronary arteries and is a leading cause of death. Inflammation is …
plaques in the walls of the coronary arteries and is a leading cause of death. Inflammation is …
Targeting the residual cardiovascular risk by specific anti-inflammatory interventions as a therapeutic strategy in atherosclerosis
A Hafiane, SS Daskalopoulou - Pharmacological Research, 2022 - Elsevier
Chronic subclinical inflammation is a key process in the pathogenesis of atherosclerotic
cardiovascular disease (ASCVD). Along with lipids, inflammation is essential for the initiation …
cardiovascular disease (ASCVD). Along with lipids, inflammation is essential for the initiation …
The link between inflammatory disorders and coronary heart disease: a look at recent studies and novel drugs in development
H Teague, NN Mehta - Current atherosclerosis reports, 2016 - Springer
Inflammation is a critical component in the development of coronary heart disease (CHD),
specifically in the process of atherogenesis. Human translational and preclinical studies …
specifically in the process of atherogenesis. Human translational and preclinical studies …
Atherosclerosis and inflammation: overview and updates
GR Geovanini, P Libby - Clinical science, 2018 - portlandpress.com
The concept that inflammation participates pivotally in the pathogenesis of atherosclerosis
and its complications has gained considerable attention, but has not yet entered clinical …
and its complications has gained considerable attention, but has not yet entered clinical …
Inflammation and cardiovascular disease: from pathogenesis to therapeutic target
E Golia, G Limongelli, F Natale, F Fimiani… - Current atherosclerosis …, 2014 - Springer
Atherosclerosis represents the most common pathological substrate of coronary heart
disease (CHD), and the characterization of the disease as a chronic low-grade inflammatory …
disease (CHD), and the characterization of the disease as a chronic low-grade inflammatory …