Inflammatory processes in cardiovascular disease: a route to targeted therapies

N Ruparelia, JT Chai, EA Fisher… - Nature reviews …, 2017 - nature.com
Inflammatory processes are firmly established as central to the development and
complications of cardiovascular diseases. Elevated levels of inflammatory markers have …

The emerging role of inflammation in cardiovascular disease

BK Martinez, CM White - Annals of Pharmacotherapy, 2018 - journals.sagepub.com
Objective: To review the role of inflammatory suppression in patients with atherosclerotic
cardiovascular disease (ASCVD) with a focus on the interleukin-1β blocker canakinumab …

Atherosclerosis and inflammation. New therapeutic approaches

J Pedro-Botet, E Climent, D Benaiges - Medicina Clínica (English Edition), 2020 - Elsevier
The recognition of atherogenesis as an active process rather than a passive cholesterol
storage disease has underlined key inflammatory mechanisms. Hence, innate and adaptive …

Management of inflammation in cardiovascular diseases

SK Goswami, P Ranjan, RK Dutta, SK Verma - Pharmacological research, 2021 - Elsevier
Cardiovascular disease is the leading cause of morbidity and mortality world-wide. Recently,
the role of inflammation in the progression of diseases has significantly attracted …

[HTML][HTML] Inflammation in atherosclerosis

S Taleb - Archives of cardiovascular diseases, 2016 - Elsevier
Atherosclerosis is an inflammatory disease within the arterial wall that is responsible for
several important adverse vascular events, including coronary artery disease, myocardial …

Inflammation and atherosclerosis

MH Shishehbor, DL Bhatt - Current Atherosclerosis Reports, 2004 - Springer
Inflammation plays a pivotal role in all stages of atherogenesis, from foam cell to plaque
formation to rupture and ultimately to thrombosis. Insight gained from recent basic and …

Inflammatory related cardiovascular diseases: from molecular mechanisms to therapeutic targets

C Sardu, G Paolisso, R Marfella - Current pharmaceutical …, 2020 - benthamdirect.com
Inflammation is a pathogenic response to multiple factors, that causes over-activation of
different molecules and pro-inflammatory cellular lines. Different behavioral factors and risk …

Atherosclerosis is an inflammatory disease which lacks a common anti-inflammatory therapy: how human genetics can help to this issue. A narrative review

C Fava, M Montagnana - Frontiers in Pharmacology, 2018 - frontiersin.org
Atherosclerosis is a multifactorial disease triggered and sustained by different risk factors
such as dyslipidemia, arterial hypertension, diabetes mellitus, smoke, etc. Since a couple of …

Targeting cardiovascular inflammation: next steps in clinical translation

PR Lawler, DL Bhatt, LC Godoy… - European heart …, 2021 - academic.oup.com
Systemic vascular inflammation plays multiple maladaptive roles which contribute to the
progression and destabilization of atherosclerotic cardiovascular disease (ASCVD). These …

Inflammation: a novel therapeutic target/direction in atherosclerosis

B Li, W Li, X Li, H Zhou - Current Pharmaceutical Design, 2017 - ingentaconnect.com
Over the past two decades, the viewpoint of atherosclerosis has been replaced gradually by
a lipiddriven, chronic, low-grade inflammatory disease of the arterial wall. Current treatment …