Decades of research have established atherosclerosis as an inflammatory disease. Only
recently though, clinical trials provided proof-of-concept evidence for the efficacy of anti …

Evidence suggests that inflammation plays an important role in atherosclerosis and the
consequent clinical presentation, including stable coronary artery disease (CAD) and acute …

Atherosclerosis, the major cause of cardiovascular disease (CVD), is a chronic inflammatory
condition with immune competent cells in lesions producing mainly pro-inflammatory …

The concept that inflammation governs atherosclerosis and its complications has provided a
new unifying hypothesis of the links between risk factors and the cellular and molecular …

Background Inflammation is a risk factor for cardiovascular disease (CVD), and particular
inflammatory parameters can be used to predict the incidence of CVD. The aim of this study …

Inflammation drives coronary artery disease and atherosclerosis implications. Lipoprotein
entry, retention, and oxidative modification cause endothelial damage, triggering innate and …

Recent clinical trials have now firmly established that inflammation participates causally in
human atherosclerosis. These observations point the way toward novel treatments that add …

For more than 20 years, our understanding of the biology of atherosclerosis has
incorporated the so-called inflammatory hypothesis. 1, 2 Inflammatory cells and signals drive …

Atherosclerotic cardiovascular disease is a leading cause of death in much of the world.
Adoption of a healthy lifestyle and cholesterol lowering are the key measures used to …

The association between thrombosis and acute coronary syndromes is well established.
Inflammation and activation of innate and adaptive immunity are another important factor …