Schizophrenia patients have prominent deficits in information processing that can be
detected by measures of prepulse inhibition (PPI) of the startle response. Deficient PPI in …

BACKGROUND: Prepulse inhibition (PPI) is the normal suppression of the startle reflex
when an intense startling stimulus is preceded by a barely detectable prepulse. Habituation …

Background: Schizophrenics show deficits in sensorimotor gating, as measured by prepulse
inhibition of acoustic startle (PPI). The goal of this investigation is to further characterize PPI …

Deficits in sensorimotor gating as assessed by prepulse inhibition (PPI) of the startle reflex
have been reported in schizophrenia. However, the state or trait nature of these deficits and …

Recent years have seen a dramatic growth in the number of studies using prepulse
inhibition (PPI) paradigms to index information processing deficits in schizophrenia. There …

Individuals with schizophrenia are known to show deficits in prepulse inhibition (PPI) of the
startle response. PPI refers to a response suppression in reaction to a strong startling …

The effects of prepulse stimuli of different intensities in inhibiting the startle reflex was
assessed in 14 age-matched and gender-matched schizophrenic patients and 14 normal …

OBJECTIVE: Information processing, inhibitory, and gating deficits in human and animal
model studies of schizophrenia are demonstrated by using prepulse inhibition of the startle …

Rationale: Prepulse inhibition (PPI) of the startle reflex is a powerful tool for investigating
sensorimotor gating in both animals and humans. Evidence of impaired PPI in patients with …

BACKGROUND: Disturbances in sensorimotor gating measured by prepulse inhibition of the
startle response (PPI) have frequently been reported in medicated and unmedicated …