[PDF][PDF] mRNA-based COVID-19 vaccine boosters induce neutralizing immunity against SARS-CoV-2 Omicron variant

WF Garcia-Beltran, KJS Denis, A Hoelzemer, EC Lam… - Cell, 2022 - cell.com
Recent surveillance has revealed the emergence of the SARS-CoV-2 Omicron variant (BA.
1/B. 1.1. 529) harboring up to 36 mutations in spike protein, the target of neutralizing …

Omicron-specific mRNA vaccine induced potent neutralizing antibody against Omicron but not other SARS-CoV-2 variants

IJ Lee, CP Sun, PY Wu, YH Lan, IH Wang, WC Liu… - BioRxiv, 2022 - biorxiv.org
The emerging SARS-CoV-2 variants of concern (VOC) harbor mutations associated with
increasing transmission and immune escape, hence undermine the effectiveness of current …

[HTML][HTML] mRNA booster immunization elicits potent neutralizing serum activity against the SARS-CoV-2 Omicron variant

H Gruell, K Vanshylla, P Tober-Lau, D Hillus… - Nature medicine, 2022 - nature.com
The Omicron variant of SARS-CoV-2 is causing a rapid increase in infections across the
globe. This new variant of concern carries an unusually high number of mutations in key …

[PDF][PDF] mRNA-1273 and BNT162b2 mRNA vaccines have reduced neutralizing activity against the SARS-CoV-2 omicron variant

VV Edara, KE Manning, M Ellis, L Lai, KM Moore… - Cell Reports …, 2022 - cell.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) omicron variant
emerged in November 2021 and consists of several mutations within the spike. We use …

[HTML][HTML] Neutralizing antibodies against the SARS-CoV-2 Delta and Omicron variants following heterologous CoronaVac plus BNT162b2 booster vaccination

E Pérez-Then, C Lucas, VS Monteiro, M Miric… - Nature medicine, 2022 - nature.com
The recent emergence of the SARS-CoV-2 Omicron variant is raising concerns because of
its increased transmissibility and its numerous spike mutations, which have the potential to …

[HTML][HTML] SARS-CoV-2 Omicron neutralization by therapeutic antibodies, convalescent sera, and post-mRNA vaccine booster

S Lusvarghi, SD Pollett, SN Neerukonda, W Wang… - BioRxiv, 2021 - ncbi.nlm.nih.gov
The rapid spread of the highly contagious Omicron variant of SARS-CoV-2 along with its
high number of mutations in the spike gene has raised alarm about the effectiveness of …

Neutralizing antibody responses elicited by SARS-CoV-2 mRNA vaccination wane over time and are boosted by breakthrough infection

JP Evans, C Zeng, C Carlin, G Lozanski… - Science Translational …, 2022 - science.org
The waning efficacy of SARS-CoV-2 vaccines, combined with the continued emergence of
variants resistant to vaccine-induced immunity, has reignited debate over the need for …

[HTML][HTML] Three exposures to the spike protein of SARS-CoV-2 by either infection or vaccination elicit superior neutralizing immunity to all variants of concern

PR Wratil, M Stern, A Priller, A Willmann, G Almanzar… - Nature medicine, 2022 - nature.com
Infection-neutralizing antibody responses after severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection or coronavirus disease 2019 vaccination are an …

[HTML][HTML] Vaccines elicit highly cross-reactive cellular immunity to the SARS-CoV-2 omicron variant

J Liu, A Chandrashekar, D Sellers, J Barrett, M Lifton… - MedRxiv, 2022 - ncbi.nlm.nih.gov
The highly mutated SARS-CoV-2 Omicron (B. 1.1. 529) variant has been shown to evade a
substantial fraction of neutralizing antibody responses elicited by current vaccines that …

[HTML][HTML] Omicron BA. 1 and BA. 2 neutralizing activity elicited by a comprehensive panel of human vaccines

JE Bowen, KR Sprouse, AC Walls, IG Mazzitelli… - BioRxiv, 2022 - ncbi.nlm.nih.gov
Abstract The SARS-CoV-2 Omicron variant of concern comprises three sublineages
designated BA. 1, BA. 2, and BA. 3, with BA. 2 steadily replacing the globally dominant BA …