Tissue engineering scaffolds have emerged as a powerful tool within regenerative medicine.
These materials are being designed to create environments that promote regeneration …

Smart biomaterials have the ability to respond to changes in physiological parameters and
exogenous stimuli and continue to impact many aspects of modern medicine. Smart …

Immune cells can sense and respond to biophysical cues—from dynamic forces to spatial
features—during their development, activation, differentiation and expansion. These …

Although most tissue types are capable of some form of self-repair and regeneration, injuries
that are larger than a critical threshold or those occurring in the setting of certain diseases …

The host response to biomaterials has been studied for decades. Largely, the interaction of
host immune cells, macrophages in particular, with implanted materials has been …

The perspectives of regenerative medicine are still severely hampered by the host response
to biomaterial implantation, despite the robustness of technologies that hold the promise to …

The immune system is traditionally considered from the perspective of defending against
bacterial or viral infections. However, foreign materials like implants can also illicit immune …

Vaccines and immunotherapies have provided enormous improvements for public health,
but there are fundamental disconnects between where most studies are performed—in cell …

An immune response involves the action of all types of macrophages, classically activated
subtype (M1) in the early inflammatory phase and regulatory and wound-healing subtypes …

Engineered cell instructive microenvironments with the ability to stimulate specific cellular
responses are a topic of high interest in the fabrication and development of biomaterials for …