Repurposing of plant alkaloids for cancer therapy: Pharmacology and toxicology
Drug repurposing (or repositioning) is an emerging concept to use old drugs for new
treatment indications. Phytochemicals isolated from medicinal plants have been largely …
treatment indications. Phytochemicals isolated from medicinal plants have been largely …
Alkaloids for cancer prevention and therapy: Current progress and future perspectives
A Mondal, A Gandhi, C Fimognari, AG Atanasov… - European journal of …, 2019 - Elsevier
Alkaloids are important chemical compounds that serve as a rich source for drug discovery.
Numerous alkaloids screened from medicinal plants and herbs showed antiproliferative and …
Numerous alkaloids screened from medicinal plants and herbs showed antiproliferative and …
Update and new insights on future cancer drug candidates from plant-based alkaloids
M Tilaoui, H Ait Mouse, A Zyad - Frontiers in Pharmacology, 2021 - frontiersin.org
Cancer is a complex multifactorial disease that results from alterations in many physiological
and biochemical functions. Over the last few decades, it has become clear that cancer cells …
and biochemical functions. Over the last few decades, it has become clear that cancer cells …
Therapeutic role of alkaloids and alkaloid derivatives in cancer management
Cancer is a neoplastic disease that remains a global challenge with a reported prevalence
that is increasing annually. Though existing drugs can be applied as single or combined …
that is increasing annually. Though existing drugs can be applied as single or combined …
[HTML][HTML] Anticancer alkaloids from trees: Development into drugs
T Isah - Pharmacognosy reviews, 2016 - ncbi.nlm.nih.gov
Trees have made an enormous phytochemical contribution in anticancer drugs'
development more than any other life form. The contributions include alkaloids that are …
development more than any other life form. The contributions include alkaloids that are …
Emerging cytotoxic alkaloids in the battle against cancer: Overview of molecular mechanisms
Considered as the second deadliest disease globally, cancer has captured the attention of
researchers who have been trying with perseverance to decode its hidden aspects, to find …
researchers who have been trying with perseverance to decode its hidden aspects, to find …
Drug repurposing in cancer
L Sleire, HE Førde, IA Netland, L Leiss, BS Skeie… - Pharmacological …, 2017 - Elsevier
Cancer is a major health issue worldwide, and the global burden of cancer is expected to
increase in the coming years. Whereas the limited success with current therapies has driven …
increase in the coming years. Whereas the limited success with current therapies has driven …
Alkaloids isolated from natural herbs as the anticancer agents
Alkaloids are important chemical compounds that serve as a rich reservoir for drug
discovery. Several alkaloids isolated from natural herbs exhibit antiproliferation and …
discovery. Several alkaloids isolated from natural herbs exhibit antiproliferation and …
Repurposing of drugs: An attractive pharmacological strategy for cancer therapeutics
A Kirtonia, K Gala, SG Fernandes, G Pandya… - Seminars in cancer …, 2021 - Elsevier
Human malignancies are one of the major health-related issues though out the world and
anticipated to rise in the future. The development of novel drugs/agents requires a huge …
anticipated to rise in the future. The development of novel drugs/agents requires a huge …
Old wine in new bottles: Drug repurposing in oncology
M Antoszczak, A Markowska, J Markowska… - European Journal of …, 2020 - Elsevier
Increasing costs, much time consumption and high risk of failure associated with the process
of de novo development of new anticancer drugs have prompted the pharmaceutical …
of de novo development of new anticancer drugs have prompted the pharmaceutical …