A systematic review of the pharmacology, toxicology and pharmacokinetics of matrine

L You, C Yang, Y Du, W Wang, M Sun, J Liu… - Frontiers in …, 2020 - frontiersin.org
Matrine (MT) is a naturally occurring alkaloid and an bioactive component of Chinese herbs,
such as Sophora flavescens and Radix Sophorae tonkinensis. Emerging evidence suggests …

Matrine: a promising natural product with various pharmacological activities

H Zhang, L Chen, X Sun, Q Yang, L Wan… - Frontiers in …, 2020 - frontiersin.org
Matrine is an alkaloid isolated from the traditional Chinese medicine Sophora flavescens
Aiton. At present, a large number of studies have proved that matrine has an anticancer …

Matrine exerts pharmacological effects through multiple signaling pathways: a comprehensive review

Y Lin, F He, L Wu, Y Xu, Q Du - Drug Design, Development and …, 2022 - Taylor & Francis
As The main effective monomer of the traditional Chinese medicine Sophora flavescens Ait,
matrine has a broad scope of pharmacological activities such as anti-tumor, anti …

Matrine: A review of its pharmacology, pharmacokinetics, toxicity, clinical application and preparation researches

X Li, Z Tang, L Wen, C Jiang, Q Feng - Journal of Ethnopharmacology, 2021 - Elsevier
Ethnopharmacological relevance “Dogel ebs” was known as Sophora flavescens Ait., which
has been widely utilized in the clinical practice of traditional Chinese Mongolian herbal …

Research progress of matrine's anticancer activity and its molecular mechanism

F Chen, Y Pan, J Xu, B Liu, H Song - Journal of Ethnopharmacology, 2022 - Elsevier
Background and ethnopharmacological relevance: Matrine (MT), a type of alkaloid extracted
from the Sophora family of traditional Chinese medicine, has been documented to exert a …

Research advances on matrine

XY Sun, LY Jia, Z Rong, X Zhou, LQ Cao, AH Li… - Frontiers in …, 2022 - frontiersin.org
Matrine is an alkaloid extracted from traditional Chinese herbs including Sophora
flavescentis, Sophora alopecuroides, Sophora root, etc. It has the dual advantages of …

Research advances on anticancer activities of matrine and its derivatives: An updated overview

H ur Rashid, Y Xu, Y Muhammad, L Wang… - European journal of …, 2019 - Elsevier
Cancer is the second leading cause of mortality, only overcome by cardiovascular diseases,
and has caused more than 8.7 million deaths in 2015 all over the world. This figure is …

Advance in the pharmacological research on matrine

M Liu, X Liu, J Cheng - China Journal of Chinese Materia …, 2003 - pesquisa.bvsalud.org
ABSTRACT< p>< b> OBJECTIVE</b> The progress in the research on matrine was involved
to provide references for the exploitation and utilization of the matrine.</p>< p>< b> …

Research progress of natural Matrine compounds and synthetic Matrine derivatives

J Li, S Wei, D Marabada, Z Wang, Q Huang - Molecules, 2023 - mdpi.com
Matrine is a quinoline alkaloid extracted and separated from the dried root, fruit, and other
parts of the plant Sophora flavescens using an organic solvent. Matrine exhibits a variety of …

Anticancer advances of matrine and its derivatives

J Yong, X Wu, C Lu - Current pharmaceutical design, 2015 - ingentaconnect.com
As the second leading cause of death in the world, the total number caused by cancer in
2008 is 1.4 million. The great cancer incidence worldwide increases the search for new …