Understanding the effects of mesenchymal stromal cell therapy for treating osteoarthritis using an in vitro co-culture model
Osteoarthritis (OA) is a leading cause of chronic pain and disability, for which there is no
cure. Mesenchymal stromal cells (MSCs) have been used in clinical trials for treating OA due …
cure. Mesenchymal stromal cells (MSCs) have been used in clinical trials for treating OA due …
[HTML][HTML] Culture-expanded mesenchymal stromal cell therapy: does it work in knee osteoarthritis? A pathway to clinical success
Osteoarthritis (OA) is a degenerative multifactorial disease with concomitant structural,
inflammatory, and metabolic changes that fluctuate in a temporal and patient-specific …
inflammatory, and metabolic changes that fluctuate in a temporal and patient-specific …
Review of patents and commercial opportunities involving Mesenchymal Stromal Cells (MSCs) therapies in osteoarthritis
S Viswanathan… - Recent Patents on …, 2014 - ingentaconnect.com
Osteoarthritis (OA) is a degenerative joint disease that affects cartilage, subchondral bone,
the synovium and synovial fluid and has limited treatment options. With an ageing …
the synovium and synovial fluid and has limited treatment options. With an ageing …
Bone marrow mesenchymal stromal cell treatment in patients with osteoarthritis results in overall improvement in pain and symptoms and reduces synovial …
J Chahal, A Gómez-Aristizábal… - Stem cells …, 2019 - academic.oup.com
Patients with late-stage Kellgren-Lawrence knee osteoarthritis received a single intra-
articular injection of 1, 10, or 50 million bone marrow mesenchymal stromal cells (BM-MSCs) …
articular injection of 1, 10, or 50 million bone marrow mesenchymal stromal cells (BM-MSCs) …
A bioengineered in vitro osteoarthritis model with tunable inflammatory environments indicates context-dependent therapeutic potential of human mesenchymal stem …
Recently, intra-articular injections of mesenchymal stem cells (MSCs) have been used as a
treatment for early osteoarthritis (OA) due to the known immunomodulatory effects of these …
treatment for early osteoarthritis (OA) due to the known immunomodulatory effects of these …
Recent advances in mesenchymal stem/stromal cells (MSCs)‐based approaches for osteoarthritis (OA) therapy
A Hassanzadeh, N Vousooghi… - Cell Biology …, 2023 - Wiley Online Library
Recently, mesenchymal stem/stromal cells (MSCs) transplantation has been introduced as a
promising option to support cartilage structure and improve its function in preclinical models …
promising option to support cartilage structure and improve its function in preclinical models …
[HTML][HTML] Mesenchymal stromal cells for the treatment of osteoarthritis of knee joint: context and perspective
PK Gupta, C Thej - Annals of Translational Medicine, 2019 - ncbi.nlm.nih.gov
Evidence from completed preclinical and clinical studies conducted worldwide suggests that
mesenchymal stromal cells (MSCs) are a novel and promising option for the treatment of …
mesenchymal stromal cells (MSCs) are a novel and promising option for the treatment of …
[HTML][HTML] Progress in the use of mesenchymal stromal cells for osteoarthritis treatment
X Zhang, J He, W Wang - Cytotherapy, 2021 - Elsevier
Literature review of MSCs in the treatment of osteoarthritis in the past five years
Osteoarthritis (OA) is one of the most common chronic joint diseases, with prominent …
Osteoarthritis (OA) is one of the most common chronic joint diseases, with prominent …
The role of inflammation in mesenchymal stromal cell therapy in osteoarthritis, perspectives for post-traumatic osteoarthritis: a review
WF Theeuwes, MHJ van den Bosch… - …, 2021 - academic.oup.com
OA is a complex and highly prevalent degenerative disease affecting the whole joint, in
which factors like genetic predisposition, gender, age, obesity and traumas contribute to joint …
which factors like genetic predisposition, gender, age, obesity and traumas contribute to joint …
Mesenchymal stem cell therapy for osteoarthritis: practice and possible promises
N Nasiri, R Nateghi, F Zarei, S Hosseini… - Cell biology and …, 2022 - Springer
Osteoarthritis (OA) is a common progressively degenerative joint disease that affects more
than 300 million people worldwide. OA is manifested by articular cartilage degradation …
than 300 million people worldwide. OA is manifested by articular cartilage degradation …