Neutrophils: Cinderella of innate immune system
Neutrophils are the first line of innate immune defense against infectious diseases.
However, since their discovery by Elie Metchnikoff, they have always been considered …
However, since their discovery by Elie Metchnikoff, they have always been considered …
Neutrophils as protagonists and targets in chronic inflammation
O Soehnlein, S Steffens, A Hidalgo… - Nature Reviews …, 2017 - nature.com
Traditionally, neutrophils have been acknowledged to be the first immune cells that are
recruited to an inflamed tissue and have mainly been considered in the context of acute …
recruited to an inflamed tissue and have mainly been considered in the context of acute …
Neutrophil secretion products regulate anti-bacterial activity in monocytes and macrophages
O Soehnlein, E Kenne, P Rotzius… - Clinical & …, 2008 - academic.oup.com
Macrophages represent a multi-functional cell type in innate immunity that contributes to
bacterial clearance by recognition, phagocytosis and killing. In acute inflammation …
bacterial clearance by recognition, phagocytosis and killing. In acute inflammation …
Interferon‐γ activation of polymorphonuclear neutrophil function
TN Ellis, BL Beaman - Immunology, 2004 - Wiley Online Library
As current research illuminates the dynamic interplay between the innate and acquired
immune responses, the interaction and communication between these two arms has yet to …
immune responses, the interaction and communication between these two arms has yet to …
The diverse biological functions of neutrophils, beyond the defense against infections
F Yang, C Feng, X Zhang, J Lu, Y Zhao - Inflammation, 2017 - Springer
Polymorphonuclear neutrophils are among the first defense against infection and closely
involved in the initiation of inflammatory response. It is well recognized that this function of …
involved in the initiation of inflammatory response. It is well recognized that this function of …
Neutrophils—from bone marrow to first-line defense of the innate immune system
RF Kraus, MA Gruber - Frontiers in immunology, 2021 - frontiersin.org
Neutrophils (polymorphonuclear cells; PMNs) form a first line of defense against pathogens
and are therefore an important component of the innate immune response. As a result of …
and are therefore an important component of the innate immune response. As a result of …
TLR-stimulated neutrophils instruct NK cells to trigger dendritic cell maturation and promote adaptive T cell responses
Polymorphonuclear neutrophils (PMNs) are innate effector cells with pivotal roles in
pathogen recognition, phagocytosis, and eradication. However, their role in the …
pathogen recognition, phagocytosis, and eradication. However, their role in the …
Pathobiology of neutrophil–epithelial interactions
Polymorphonuclear neutrophils (PMN s) are innate immune system cells that play an
essential role in eradicating invading pathogens. PMN migration to sites of …
essential role in eradicating invading pathogens. PMN migration to sites of …
Cross-talk among polymorphonuclear neutrophils, immune, and non-immune cells via released cytokines, granule proteins, microvesicles, and neutrophil extracellular …
CY Tsai, SC Hsieh, CW Liu, CS Lu, CH Wu… - International Journal of …, 2021 - mdpi.com
Polymorphonuclear neutrophils (PMNs) are traditionally regarded as professional
phagocytic and acute inflammatory cells that engulf the microbial pathogens. However …
phagocytic and acute inflammatory cells that engulf the microbial pathogens. However …
Cytokines and macrophages
JM Cavaillon - Biomedicine & pharmacotherapy, 1994 - Elsevier
Macrophages, within the cytokine network, are a major source of many cytokines involved in
immune response, hematopoiesis, inflammation and many other homeostatic processes …
immune response, hematopoiesis, inflammation and many other homeostatic processes …