Various functions of mature human neutrophils are activated or potentiated by hematopoietic
growth factors or proinflammatory cytokines such as granulocyte colony-stimulating factor …

Mediators of inflammation induced by macrophages are critical for a variety of human
inflammatory disorders, such as sepsis-related multiple organ dysfunction/multiple organ …

Blood neutrophils (PMN) are usually unresponsive to CC chemokines such as monacyte
chemotactic protein-1 and macrophage inflammatory protein-1α. In rodents, the lung buildup …

Neutrophils are the first immune cells to migrate into infected tissue sites. Therefore an
important step in the initiation of an immune response is the synthesis of the neutrophil …

Neutrophils have traditionally been thought of as simple foot soldiers of the innate immune
system with a restricted set of pro-inflammatory functions. More recently, it has become …

In order for neutrophils to function effectively in host defense, they have evolved specific
attributes including the ability to migrate to the site of inflammation and release an array of …

Neutrophils are the most abundant leukocytes in the circulation, and have been regarded as
first line of defense in the innate arm of the immune system. They capture and destroy …

Neutrophils have long been regarded as the first line of defense against infection and one of
the main cell types involved in initiation of the inflammatory response. It is generally …

Neutrophils are versatile innate effector cells essential for immune defense but also
responsible for pathologic inflammation. This dual role complicates therapeutic targeting …

The neutrophil (PMN) influx in the acute inflammatory response is associated with a local
increase in vascular permeability and oedema. Vascular endothelial growth factor (VEGF), a …