Although it was originally thought that amongst blood cells, monocytes and lymphocytes
were the predominant sources of cytokines, it is now evident that cytokines are generated by …

Chemokines are recognized as the most critical mediators for selective neutrophil
recruitment during inflammatory conditions. Furthermore, they are considered fundamental …

In inflammatory conditions such as RA, the neutrophil has tended to be dismissed as a short-
lived, terminally differentiated, irrelevant bystander cell. However, this is clearly not the case …

Many lung diseases are characterized by neutrophil-dominated inflammation; therefore, an
understanding of neutrophil function is of considerable importance to respiratory physicians …

Neutrophils are the most abundant circulating leukocytes, being the first line of defence
against bacterial and fungal infections. However, neutrophils also contribute to tissue …

Increasing data from the literature point to a neutrophil-mediated role via cytokine production
in several aspects of mammalian biology, including angiogenesis. In such regard …

Inflammatory monocyte-derived effector cells play an important role in the pathogenesis of
numerous inflammatory diseases. However, no treatment option exists that is capable of …

Neutrophil (PMN) mobilization to sites of insult is critical for host defense and requires
transendothelial migration (TEM). TEM involves several well-studied sequential adhesive …

Neutrophils are the most abundant circulating and first-responding innate myeloid cells and
have so far been underestimated in the context of multiple sclerosis (MS). MS is the most …

Antimicrobial human neutrophil peptides (HNPs) play a pivotal role in innate host defense
against a broad spectrum of prokaryotic pathogens. In addition, HNPs modulate cellular …