Background/Aims: Recently, several cells found within the liver have been reported to derive
from bone marrow (BM). This study sought to examine the commitment of BM cells to hepatic …

Increasing evidence in recent years has suggested that B cells act as a crucial regulator in
autoimmune diseases. However, little is known about their role in autoimmune hepatitis …

Activated hepatic stellate cells (HSCs) are the main producers of extracellular matrix in the
fibrotic liver and are involved in the regulation of hepatic inflammation. The aim of this study …

Hepatic fibrosis is a dynamic process characterized by the net accumulation of extracellular
matrix resulting from chronic liver injury of any aetiology, including viral infection, alcoholic …

T” RESPONSE to tissue injury comprises a series of events which are relatively similar
irrespective of the tissue involved, although each organ contains specialized cells and …

Hepatic stellate cells (HSCs) are critical mediators of immunosuppression and the
pathogenesis of hepatocellular carcinoma (HCC). Our previous work indicates that HSCs …

Hepatic stellate cells are liver-resident cells of star-like morphology and are located in the
space of Disse between liver sinusoidal endothelial cells and hepatocytes 1, 2. Stellate cells …

Hepatic stellate cells (HSCs) were recently postulated as a component of the prometastatic
liver microenvironment, because they can transdifferentiate into highly proliferative and …

Bone marrow-derived mesenchymal stem cells (MSCs) have been reported to prevent the
development of liver fibrosis in a number of pre-clinical studies. Marked changes in liver …

The hepatic stellate cell (HSC), after a fibrogenic stimulus, is transformed from a quiescent to
an activated phenotype, including the induction of responsiveness to a variety of agonists …