Treatment response to isotretinoin correlates with specific shifts in Cutibacterium acnes strain composition within the follicular microbiome

ZT Nolan, K Banerjee, Z Cong, SL Gettle… - Experimental …, 2023 - Wiley Online Library
There are no drugs as effective as isotretinoin for acne. Deciphering the changes in the
microbiome induced by isotretinoin in the pilosebaceous follicle of successfully treated …

Cutibacterium acnes phylotypes diversity loss: a trigger for skin inflammatory process

MA Dagnelie, S Corvec, M Saint‐Jean… - Journal of the …, 2019 - Wiley Online Library
Background Acne has long been understood as a multifactorial chronic inflammatory
disease of the pilosebaceous follicle, where Cutibacterium acnes (subdivided into six main …

The role of the skin microbiota in acne pathophysiology

S Ramasamy, E Barnard… - British Journal of …, 2019 - academic.oup.com
Background The role of skin microbiota in acne remains to be fully elucidated. Initial culture‐
based investigations were hampered by growth rate and selective media bias. Even with …

Evaluation of CRISPR diversity in the human skin microbiome for personal identification

K Toyomane, R Yokota, K Watanabe, T Akutsu… - Msystems, 2021 - Am Soc Microbiol
The highly personalized human skin microbiome may serve as a viable marker in personal
identification. Amplicon sequencing resolution using 16S rRNA cannot identify bacterial …

Cutibacterium acnes: Much ado about maybe nothing much

MAM van Steensel, BC Goh - Experimental Dermatology, 2021 - Wiley Online Library
Cutibacterium acnes (also known as Propionibacterium acnes) has long been implicated in
the pathogenesis of acne, inspiring both therapeutic and personal care approaches aiming …

Interaction of Cutibacterium ( formerly Propionibacterium) acnes with bone cells: a step toward understanding bone and joint infection development

GG Aubin, M Baud'huin, JP Lavigne, R Brion… - Scientific Reports, 2017 - nature.com
Cutibacterium acnes (formerly Propionibacterium acnes) is recognized as a pathogen in
foreign-body infections (arthroplasty or spinal instrumentation). To date, the direct impact of …

Strains to go: interactions of the skin microbiome beyond its species

R Caldwell, W Zhou, J Oh - Current opinion in microbiology, 2022 - Elsevier
Highlights•The human skin microbiome differs between and within individuals.•Ubiquitous
bacteria S. epidermidis and C. acnes have major roles in skin immunity and …

Cutibacterium acnes (Propionibacterium acnes) 16S rRNA genotyping of microbial samples from possessions contributes to owner identification

J Yang, T Tsukimi, M Yoshikawa, K Suzuki, T Takeda… - Msystems, 2019 - Am Soc Microbiol
The human skin surface harbors huge numbers of microbes. The skin microbiota interacts
with its host and forms a skin microbiome profile that is specific for each individual. It has …

[HTML][HTML] Different Propionibacterium acnes phylotypes induce distinct immune responses and express unique surface and secreted proteomes

Y Yu, J Champer, GW Agak, S Kao, RL Modlin… - Journal of Investigative …, 2016 - Elsevier
Propionibacterium acnes is a skin commensal bacterium that contributes to the development
of acne vulgaris and other infections. Recent work revealed that P. acnes clinical isolates …

Classification of Cutibacterium acnes at phylotype level by MALDI-MS proteotyping

K Teramoto, T Okubo, Y Yamada, S Sekiya… - Proceedings of the …, 2019 - jstage.jst.go.jp
Cutibacterium acnes is a major commensal human skin bacteria. It is a producer of propionic
acids that maintain skin acidic pH to inhibit the growth of pathogens. On the other hand, it is …