ABSTRACT Background. Red blood cells (RBCs) must deform to pass the smallest
capillaries of the microcirculation. Available techniques for measuring RBC deformability …

Abstract Background Red blood cells (RBCs) have to deform markedly to pass through the
smallest capillaries of the microcirculation. Techniques for measuring RBC deformability …

Background. The deformability of red blood cells (RBCs) is of great importance for the
conservation of oxygen delivery in the microcirculation. Even a small fraction of rigid cells is …

Human red blood cells (RBCs) or erythrocytes have remarkable deformability. Upon external
forces, RBCs undergo large mechanical deformation without rupture, and they restore to …

Cell-deformability characterization involves general measurement of highly complex
relationships between cell biology and physical forces to which the cell is subjected. The …

The resistance to blood flow is a function of the rheological properties of blood as well as the
geometric features of blood vessels. While circulatory investigations generally aim at …

Decreased red cell deformability is characteristic of several disorders. In some cases, the
extent of defective deformability can predict severity of disease or occurrence of serious …

Background: Red blood cell (RBC) rheology is altered in different diseases, including acute
conditions such as patients in intensive care units (ICU) with sepsis or with an inflammatory …

Normal erythrocytes are highly deformable and this greatly facilitates blood flow in the
narrow channels of the circulation, compensating for the effect of the much less deformable …

Ektacytometry is frequently used to study red blood cell (RBC) deformability. This method is
capable of measuring RBC deformation under a wide range of shear stresses, and the …