Nanoparticles derived from the natural antioxidant rosmarinic acid ameliorate acute inflammatory bowel disease
Rosmarinic acid (RA), one of the most important polyphenol-based antioxidants, has
received growing interest because of its bioactive properties, including anti-inflammatory …
received growing interest because of its bioactive properties, including anti-inflammatory …
Anti-inflammatory effects of rosmarinic acid-loaded nanovesicles in acute colitis through modulation of NLRP3 inflammasome
S Marinho, M Illanes, J Ávila-Román, V Motilva… - Biomolecules, 2021 - mdpi.com
Ulcerative colitis (UC), one of the two main types of inflammatory bowel disease, has no
effective treatment. Rosmarinic acid (RA) is a polyphenol that, when administered orally, is …
effective treatment. Rosmarinic acid (RA) is a polyphenol that, when administered orally, is …
Colon-targeted oral nanoparticles based on ROS-scavenging hydroxyethyl starch-curcumin conjugates for efficient inflammatory bowel disease therapy
C Xu, S Chen, C Chen, Y Ming, J Du, J Mu… - International Journal of …, 2022 - Elsevier
Co-delivery of anti-inflammatory drugs and reactive oxygen species (ROS) scavengers by
stimuli-responsive oral nanoparticles is deemed to be a favorable strategy for inflammatory …
stimuli-responsive oral nanoparticles is deemed to be a favorable strategy for inflammatory …
Antioxidant nanotherapies for the treatment of inflammatory diseases
CW Li, LL Li, S Chen, JX Zhang, WL Lu - Frontiers in Bioengineering …, 2020 - frontiersin.org
Reactive oxygen species (ROS) are essential in regulating various physiological functions.
However, overproduction of ROS is implicated in the pathogenesis of various inflammatory …
However, overproduction of ROS is implicated in the pathogenesis of various inflammatory …
The progression of inorganic nanoparticles and natural products for inflammatory bowel disease
There is a growing body of evidence indicating a close association between inflammatory
bowel disease (IBD) and disrupted intestinal homeostasis. Excessive production of reactive …
bowel disease (IBD) and disrupted intestinal homeostasis. Excessive production of reactive …
ROS Scavenging and inflammation-directed polydopamine nanoparticles regulate gut immunity and flora therapy in inflammatory bowel disease
M Bao, K Wang, J Li, Y Li, H Zhu, M Lu, Y Zhang… - Acta Biomaterialia, 2023 - Elsevier
Dysfunction of the intestinal mucosal immune system and dysbiosis of the intestinal
microflora can induce inflammatory bowel disease. However, drug-mediated clinical …
microflora can induce inflammatory bowel disease. However, drug-mediated clinical …
Genistein-derived ROS-responsive nanoparticles relieve colitis by regulating mucosal homeostasis
W Fan, S Zhang, Y Wu, T Lu, J Liu, X Cao… - … Applied Materials & …, 2021 - ACS Publications
Disruption of intestinal homeostasis is an important event in the development of
inflammatory bowel disease (IBD), and genistein (GEN) is a candidate medicine to prevent …
inflammatory bowel disease (IBD), and genistein (GEN) is a candidate medicine to prevent …
[HTML][HTML] ROS-responsive nanoparticles for oral delivery of luteolin and targeted therapy of ulcerative colitis by regulating pathological microenvironment
C Tan, H Fan, J Ding, C Han, Y Guan, F Zhu, H Wu… - Materials Today Bio, 2022 - Elsevier
Oxidative stress, caused by excessive production of reactive oxygen species (ROS), plays a
crucial role in the occurrence and development of ulcerative colitis (UC). We developed …
crucial role in the occurrence and development of ulcerative colitis (UC). We developed …
[HTML][HTML] Reactive oxygen species-responsive nanocarrier ameliorates murine colitis by intervening colonic innate and adaptive immune responses
Ulcerative colitis (UC) is a chronic or relapsing inflammatory disease with limited therapeutic
outcomes. Pterostilbene (PSB) is a polyphenol-based anti-oxidant that has received …
outcomes. Pterostilbene (PSB) is a polyphenol-based anti-oxidant that has received …
Ultrasmall antioxidant cerium oxide nanoparticles for regulation of acute inflammation
J Kim, G Hong, L Mazaleuskaya, JC Hsu… - … applied materials & …, 2021 - ACS Publications
Cerium oxide nanoparticles (CeONP), having potent antioxidant properties, are highly
promising nanomaterials for treatment of diseases in which oxidative stress from excessive …
promising nanomaterials for treatment of diseases in which oxidative stress from excessive …