Our previous studies have indicated that the thalamic nucleus submedius (Sm) is involved in
modulation of nociception as part of an ascending component of an endogenous analgesic …

It has been established that chemical stimulation of the inferior colliculus (IC) of laboratory
animals evokes fear-related defensive responses, which are considered panic attack-like …

The post-ictal immobility syndrome is followed by a significant increase in the nociceptive
thresholds in animals and men. In this interesting post-ictal behavioral response …

The electrical stimulation of the dorsolateral columns of the periaquedutal grey matter
(dlPAG) or deep layers of the superior colliculus (dlSC) evokes defensive behaviours …

It is well-known that the exposure of rodents to threatening environments [eg, the open arm
of the elevated-plus maze (EPM)] elicits pain inhibition. Systemic and/or intracerebral [eg …

Although 5-HT is clearly involved in spinal analgesia, its mode of action remains obscure,
perhaps because it has multiple and often opposing effects mediated by its multiple receptor …

This study examined whether the antinociception produced by electrical stimulation of
medullary raphe nuclei is mediated by activation of monoaminergic neurons projecting to …

Serotonergic mechanisms play a central role in migraine pathology. However, the region-
specific effects of serotonin (5-HT) mediated via multiple types of receptors in the nociceptive …

The antinociceptive role of spinal serotonin (5-HT) neurons descending from 5-HT cells near
the ventrolateral surface of the medulla oblongata was investigated by stimulating these …

The present study was undertaken to evaluate the potential role of 5-HT1A receptors in the
antidepressant-like effect and antinociceptive effect of venlafaxine. With this aim, the effect of …